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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Protein Kinase C inhibition ameliorates functional endothelial insulin resistance and Vascular Smooth Muscle Cell hypersensitivity to insulin in diabetic hypertensive rats

Figure 4

Analysis of vasorelaxation. A: Endothelium-dependent vasorelaxation in response to acetylcholine while vessel was pre-constricted with phenylephrine (PE). SD+V: Vehicle treated Sprague-Dawley rats. H+V: Vehicle treated DH rats. H+C: Captopril treated DH rats. H+R: RBX treated DH rats. B: Vascular relaxation in response to insulin while vessel was pre-constricted with PE. C: Endothelium-independent vasorelaxation in response to SNP while vessel was pre-constricted with PE. n = 7; *: P < 0.05 vs. vehicle treated of SD rats at the doses. #: P < 0.05 vs. vehicle treated SD rats using ANOVA.

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