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Table 2 Cardiovascular parameters: Heart rate variability (HRV) and systolic arterial pressure variability (SAPV) analysis

From: Renal denervation in an animal model of diabetes and hypertension: Impact on the autonomic nervous system and nephropathy

 

SHR (n = 7)

RD-SHR (n = 6)

STZ-SHR (n = 6)

RD-STZ-SHR (n = 5)

Heart rate (bpm)

384.82 ± 37.26

431.32 ± 36.60*

316.21 ± 5.17*

363.81 ± 12.25§#

Systolic AP (mmHg)

178.43 ± 16.07

171.03 ± 5.22

145.39 ± 8.49*

157.20 ± 26.41

Diastolic AP (mmHg)

141.17 ± 19.10

150.27 ± 13.52

116.26 ± 29.34*

118.88 ± 10.75#

Mean AP (mmHg)

160.13 ± 16.08

165.25 ± 8.89

129.22 ± 5.66*

139.90 ± 9.15#

HRV

    

HRV (ms2)

69.84 ± 37.91

55.75 ± 25.21

73.40 ± 53.30

148.39 ± 93.58§#

LF peak (Hz)

0.64 ± 0.06

0.69 ± 0.08

0.55 ± 0.10

0.54 ± 0.14#

LF absolute (ms2)

5.17 ± 5.24

1.62 ± 0.98

2.12 ± 0.97

7.38 ± 6.52§#

LF nu

26.84 ± 19.05

26.07 ± 13.63

6.98 ± 3.86*

16.58 ± 7.99

HF (Hz)

2.42 ± 0.58

2.12 ± 0.82

2.00 ± 0.56

2.31 ± 0.65

HF absolute (ms2)

14.56 ± 12.83

4.14 ± 3.09

32.11 ± 15.88*

37.22 ± 20.54#

HF nu

73.16 ± 19.05

72.90 ± 12.59

93.02 ± 3.86*

83.42 ± 7.99

LF/HF ĂŤndex

0.47 ± 0.47

0.49 ± 0.32

0.08 ± 0.05*

0.21 ± 0.11

SAPV

    

SAPV (mmHg2)

68.33 ± 36.16

61.89 ± 24.84

15.61 ± 10.26*

29.86 ± 20.69

VLF (mmHg2)

77.13 ± 54.27

38.00 ± 27.50

12.91 ± 8.11*

46.20 ± 47.03

LF (Hz)

0.44 ± 0.06

0.53 ± 0.06

0.36 ± 0.07*

0.40 ± 0.08

LF absolute (mmHg2)

18.49 ± 18.17

3.69 ± 3.10*

1.38 ± 1.38*

56.61 ± 26.75#

HF peak (Hz)

1.72 ± 0.68

2.12 ± 0.56

1.19 ± 0.22

1.52 ± 0.48

HF absolute (mmHg2)

4.67 ± 5.09

53.94 ± 17.65*

5.66 ± 5.45

6.27 ± 10.70#

αLF Índex

0.54 ± 0.16

0.86 ± 0.56

1.44 ± 0.38*

1.73 ± 1.38

  1. Data are shown as mean ± SEM. SHR: spontaneously hypertensive rats; RD-SHR: renal denervated spontaneously hypertensive rats; STZ-SHR: diabetic spontaneously hypertensive rats; RD-STZ-SHR: diabetic renal-denervated spontaneously hypertensive rats; AP: arterial pressure; n = indicates the number of animals. VLF: very low frequency; LF: low frequency; HF: high frequency. *P < 0.05 vs. H, § P < 0.05 vs. D e #P < 0.05 vs. HRD. (Two-way ANOVA; post hoc: Student Newman Keuls).