Table 2 Gender based dimorphism of PPARγ2 gene polymorphism on clinical features of the study population
PPARγ2 Pro12Ala | ||||||
|---|---|---|---|---|---|---|
Men | Women | |||||
PP (129) | XA (8) | p | PP (205) | XA (22) | p | |
Age (years) | 57 ± 14 | 57 ± 14 | 0.970 | 55 ± 13 | 51 ± 8 | 0.141 |
BMI (kg/m2) | 29.98 ± 4.75 | 31.20 ± 6.69 | 0.492 | 30.98 ± 6.19 | 34.02 ± 6.16 | 0.029 |
WAIST (cm) | 102.40 ± 12.76 | 104.19 ± 15.04 | 0.705 | 95.92 ± 14.05 | 98.61 ± 13.38 | 0.392 |
Fat Mass (kg) | 27.35 ± 10.62 | 29.16 ± 13.56 | 0.646 | 31.88 ± 12.47 | 38.08 ± 12.42 | 0.028 |
Glucose (mmol/L) | 7.1 ± 2.8 | 5.9 ± 2.1 | 0.278 | 6.1 ± 2.4 | 5.9 ± 2.4 | 0.737 |
Insulin (μUI/L)* | 7.7 (5.2-12.0) | 7.2 (4.0-14.4) | 0.778 | 7.9 (5.1-12.6) | 10.08 (8.6-15-7) | 0.210 |
HOMA Insulin Resistance* | 2.4 (1.5-3.5) | 1.9 (0.9-3.6) | 0.466 | 2.0 (1.3-3.3) | 2.4 (2.1-3.6) | 0.416 |
Systolic Blood Pressure (mmHg) | 136.93 ± 15.09 | 134.17 ± 6.65 | 0.657 | 132.38 ± 18.51 | 124.77 ± 18.67 | 0.070 |
Diastolic Blood Pressure (mmHg) | 82.57 ± 8.23 | 84.17 ± 7.36 | 0.642 | 82.33 ± 8.69 | 80.91 ± 11.41 | 0.485 |
Total Cholesterol (mmol/L) | 5.5 ± 1.5 | 5.5 ± 1.0 | 0.939 | 5.7 ± 1.3 | 6.1 ± 1.1 | 0.206 |
Triglyceride (mmol/L)* | 1.76 (1.12-2.5) | 1.3(1.05-1.9) | 0.414 | 1.37 (0.96-1.79) | 1.32 (0.96-1.93) | 0.687 |
HDL cholesterol (mmol/L) | 1.2 ± 0.3 | 1.4 ± 0.3 | 0.155 | 1.4 ± 0.3 | 1.4 ± 0.4 | 0.463 |
LDL Cholesterol (mmol/L) | 3.4 ± 1.4 | 3.4 ± 0.9 | 0.918 | 3.6 ± 1.2 | 4.0 ± 1.1 | 0.162 |