Table 1 Clinical features of the whole study population across different PPARγ2 and ACE I/D genotypes
All subjects | |||||||
|---|---|---|---|---|---|---|---|
Pro12Ala | ACE I/D | ||||||
PP (334) | XA (30) | p | DD (137) | ID (172) | II (55) | p | |
Age (years) | 56 ± 13 | 53 ± 10 | 0.200 | 56 ± 12 | 55 ± 14 | 56 ± 13 | 0.805 |
BMI (kg/m2) | 30.6 ± 5.7 | 33.2 ± 6.3 | 0.015 | 31.3 ± 6.3 | 30.4 ± 5.4 | 30.9 ± 5.5 | 0.402 |
WAIST (cm) | 98.4 ± 13.9 | 100.1 ± 13.8 | 0.528 | 99.8 ± 14.5 | 97.5 ± 13.2 | 98.7 ± 14.2 | 0.360 |
Fat Mass (kg) | 30.1 ± 11.9 | 35.7 ± 13.1 | 0.016 | 31.1 ± 12.8 | 29.9 ± 11.6 | 31.1 ± 12.2 | 0.644 |
Glucose (mmol/L) | 6.5 ± 2.6 | 5.9 ± 2.3 | 0.271 | 6.7 ± 2.9 | 6.2 ± 2.3 | 6.5 ± 2.5 | 0.22 |
Insulin (μUI/L)* | 7.8 (5.1-12.2) | 10.1 (8.0-15.6) | 0.284 | 8.0 (6.0-11.7) | 7.9 (5.0-13.0) | 8.9 (5.3-14.5) | 0.338 |
HOMA Insulin Resistance* | 2.1 (1.3-3.4) | 2.3 (1.9-3.6) | 0.668 | 2.1 (1.5-3.3) | 2.1 (1.2-3.5) | 2.4 (1.3 -3.9) | 0.816 |
Systolic Blood Pressure (mmHg) | 134.1 ± 17.4 | 126.8 ± 17.2 | 0.033 | 132.3±17.1 | 134.7±18.1 | 132.6±16.3 | 0.486 |
Diastolic Blood Pressure (mmHg) | 82.4 ± 8.5 | 81.6 ± 10.6 | 0.637 | 82.4 ± 9.2 | 82.6 ± 8.3 | 81.2 ± 8.5 | 0.612 |
Total Cholesterol (mmol/L) | 5.6 ± 1.4 | 5.9 ± 1.1 | 0.245 | 5.8 ± 1.4 | 5.7 ± 1,4 | 5.3 ± 1,2 | 0.1 |
Triglyceride (mmol/L)* | 1.46 (1.04-2.07) | 1.32 (0.99-1.93) | 0.566 | 1.54 (1.13-2.15) | 1.4 (0.99-2.01) | 1.43 (0.97-2.0) | 0.41 |
HDL cholesterol (mmol/L) | 1.3 ± 0.4 | 1.4 ± 0.3 | 0.595 | 1.3 ± 0.4 | 1.3 ± 0.4 | 1.4 ± 0.3 | 0.92 |
LDL Cholesterol (mmol/L) | 3.5 ± 1.3 | 3.8 ± 1.1 | 0.199 | 3.6 ± 1.2 | 3.6 ± 1.3 | 3.2 ± 1.1 | 0.16 |