Figure 4
Protein expression of angiotensin II type 1 receptor (C: AT 1 R, 43 kDa) and type 2 receptor (D: AT 2 R, 44 kDa) in aortic tissues. Representative blots from aortic samples in each group are shown at the top. The bar graph shows protein expression of AT1R or AT2R relative to internal control ß-actin (45 kDa) from 4 separate experiments in each group. Con: the regular diet group; Cho: the cholesterol-rich diet plus methylthiouracil group; Ros: the group on cholesterol-rich diet plus methylthiouracil and rosiglitazone treatment. Note that rosiglitazone treatment led to the marked reduction in protein expression of AT1R, while further increase in protein expression of AT2R compared with the Cho group. *P < 0.01 versus Con group; ‡P < 0.01 versus Cho group.