Angiotensin II type 1 and type 2 receptor expression in circulating monocytes of diabetic and hypercholesterolemic patients over 3-month rosuvastatin treatment

Table 2 Laboratory characteristics of patients at baseline and after three-month rosuvastatin therapy

	Diabetic patients (n = 10)			Hypercholesterolemic patients (n = 10)
	baseline	treatment	#P	baseline	treatment	#P
TC (mg/dl)	223.7 ± 34.0	168.5 ± 45.9	0.003	288.2 ± 41.0	165.5 ± 24.4	<0.001
TG (mg/dl)	165.3 ± 73.0	118.5 ± 31.5	0.012	180.9 ± 61.4	133.5 ± 58.9	0.004
HDL-c (mg/dl)	50.0 ± 2.8	50.2 ± 6.5	0.94	55.1 ± 9.9	50.7 ± 12.1	0.164
LDL-c (mg/dl)	135.7 ± 20.6	85.0 ± 25.6	<0.001	197.0 ± 34.1	88.1 ± 25.1	<0.001
ApoA (mg/dl)	128.0 ± 53.0	163.0 ± 14.4	0.69	144.5 ± 28.5	160.1 ± 55.4	0.34
ApoB (mg/dl)	117.2 ± 29.1	54.0 ± 14.9	<0.001	147.1 ± 38.8	75.1 ± 24.6	<0.001
Glucose (mg/dl)	137.7 ± 19.4	135.5 ± 31.8	0.79	98.6 ± 5.7	97.0 ± 12.9	0.77
Insulinemia (ng/ml)	14.2 ± 3.4	16.3 ± 3.5	0.63	18.8 ± 14.7	19.7 ± 17.0	0.63
AST	24.2 ± 4.3	24.0 ± 4.1	0.94	18.3 ± 5.6	17.1 ± 3.5	0.658
ALT	37.7 ± 19.2	39.2 ± 27.1	0.78	27.6 ± 12.9	21.3 ± 4.4	0.122
GGT	43.3 ± 27.2	46.5 ± 39.6	0.65	21.7 ± 5.9	20.1 ± 5.6	0.131
CK	226.8 ±113.7	212.7 ± 103.5	0.73	135.7 ± 64.9	134.4 ± 56.6	0.994
s-creatinine	0.98 ± 0.11	0.97 ± 0.10	0.89	0.98 ± 0.17	0.99 ± 0.18	0.597
GFR	76.33 ± 12.18	77.5 ± 3.56	0.79	73.22 ± 33.31	74.00 ± 12.09	0.667
hsCRP	2.94 ± 2.02	1.76 ± 0.51	0.03	1.70 ± 1.69	1.15 ± 0.79	0.350

TC = total cholesterol; TG = triglycerides; HDL-c = high density lipoprotein-cholesterol; LDL-c = low density lipoprotein-cholesterol; ApoA = Apolipoprotein A; ApoB = Apolipoprotein B; AST = aspartate aminotransferase; ALT = alanine aminotransferase; GGT = γ-glutamyl transpeptidase; CK = creatine kinase; GFR = glomerular filtration rate; hsCRP = high sensitivity C reactive protein. # Paired t test.

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