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Table 2 Clinical and laboratory measurements at baseline

From: Ipragliflozin and sitagliptin differentially affect lipid and apolipoprotein profiles in type 2 diabetes: the SUCRE study

Parameter

Ipragliflozin

Sitagliptin

P*

n

Mean/median

SD/IQR

n

Mean/median

SD/IQR

Age (year)

77

62

53–67

83

63

54–69

0.19

Height (cm)

77

162.7

8.3

83

161.7

8.4

0.45

Body weight (kg)†

77

69.0

61.8–74.5

83

65.3

59.0–72.8

0.07

Systolic BP (mmHg)

77

138

132–140

83

132

128–138

0.002

Diastolic BP (mmHg)

77

78

76–81

83

76

74–81

0.14

FPG (mmol/L)

62

8.5

7.2–9.8

70

8.6

7.5–10.0

0.34

Insulin (pmol/L)

62

62

39–88

69

58

34–110

0.72

HbA1c (%)

77

7.5

7.1–7.9

82

7.4

7.0–8.0

0.58

GA (%)

77

19.5

17.6–21.0

82

19.6

17.3–22.1

0.61

Lipids

       

 TC (mg/dL)†

77

223.9

39.8

82

221.3

38.5

0.68

 LDL-C (mg/dL)†

58

137.6

33.1

68

131.4

33.4

0.29

 HDL-C (mg/dL)

77

46

40–54

82

48

41–61

0.15

 TG (mg/dL)

62

161

121–250

70

184

109–239

0.65

Apolipoproteins

       

 AI (mg/dL)†

77

141.6

23.1

82

146.0

27.7

0.28

 AII (mg/dL)

77

29.3

27.1–31.9

82

30.0

26.6–33.3

0.97

 B (mg/dL)

77

114

99–139

82

111

94–130

0.54

 B48 (µg/L)

77

6.2

3.1–9.7

82

5.6

4.2–10.9

0.58

 CII (mg/dL)

77

5.7

4.2–7.6

82

5.1

3.5–6.9

0.13

 CIII (mg/dL)

77

11.9

8.9–15.2

82

11.5

8.8–14.3

0.61

 E (mg/dL)

77

5.0

4.1–6.1

82

5.0

4.0–5.6

0.57

Cr (mg/dL)

77

0.69

0.57–0.78

82

0.69

0.55–0.83

0.95

CysC (mg/L)

77

0.89

0.78–1.04

81

0.89

0.79–1.01

0.80

Cr-based eGFR (mL/min/1.73 m2)†

77

82.4

17.4

82

81.3

18.2

0.72

CysC-based eGFR†

77

81.8

17.1

81

81.8

18.8

0.93

UACR (mg/g Cr)

77

22.9

10.2–71.5

80

13.6

7.3–54.2

0.12

  1. *, P < 0.05 indicates the statistical significance based on unpaired t-test or Wilcoxon rank-sum test for the between-group difference
  2. †, Mean and standard deviation (SD) are presented; otherwise, median and interquartile range (IQR) are presented
  3. BP, blood pressure; Cr, creatinine; CysC, cystatin C; FPG, fasting plasma glucose; GA, glycoalbumin; eGFR: estimated glomerular flitration rate, HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides; UACR, urine albumin-to-creatinine ratio