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Table 1 Baseline characteristics participants according to body mass index

From: Interacting and joint effects of triglyceride-glucose index (TyG) and body mass index on stroke risk and the mediating role of TyG in middle-aged and older Chinese adults: a nationwide prospective cohort study

Characteristic

Overall (n = 8231)

BMI (kg/m2)

P value a

 < 24.0 (n = 4882)

24.0–27.9 (n = 2414)

 ≥ 28.0 (n = 935)

Age, years

59.23 ± 9.32

60.38 ± 9.62

57.81 ± 8.67

56.88 ± 8.36

 < 0.001

 < 60

4571 (55.5%)

2495 (51.1%)

1468 (60.8%)

608 (65.0%)

 

 ≥ 60

3660 (44.5%)

2387 (48.9%)

946 (39.2%)

327 (35.0%)

 

Gender

    

 < 0.001

Male

3815 (46.3%)

2525 (51.7%)

981 (40.6%)

309 (33.0%)

 

Female

4416 (53.7%)

2357 (48.3%)

1433 (59.4%)

626 (67.0%)

 

Marital status

    

 < 0.001

Marred

6857 (83.3%)

3955 (81.0%)

2090 (86.6%)

812 (86.8%)

 

Other

1374 (16.7%)

927 (19.0%)

324 (13.4%)

123 (13.2%)

 

Residence

    

 < 0.001

Urban

2936 (35.7%)

1485 (30.4%)

1015 (42.0%)

436 (46.6%)

 

Rural

5295 (64.3%)

3397 (69.6%)

1399 (58.0%)

499 (53.4%)

 

Education level

    

 < 0.001

No formal education

2461 (29.9%)

1558 (31.9%)

651 (27.0%)

252 (27.0%)

 

Primary school

3345 (40.6%)

2060 (42.2%)

926 (38.4%)

359 (38.4%)

 

Middle or high school

2175 (26.4%)

1147 (23.5%)

735 (30.4%)

293 (31.3%)

 

College or above

250 (3.0%)

117 (2.4%)

102 (4.2%)

31 (3.3%)

 

Smoking status b

    

 < 0.001

Never

5009 (60.9%)

2702 (55.3%)

1619 (67.1%)

688 (73.6%)

 

Former

717 (8.7%)

393 (8.0%)

236 (9.8%)

88 (9.4%)

 

Current

2483 (30.2%)

1769 (36.2%)

555 (23.0%)

159 (17.0%)

 

Drinking status b

    

 < 0.001

Never

4818 (58.5%)

2706 (55.4%)

1495 (61.9%)

617 (66.0%)

 

Former

684 (8.3%)

414 (8.5%)

183 (7.6%)

87 (9.3%)

 

Current

2725 (33.1%)

1759 (36.0%)

735 (30.4%)

231 (24.7%)

 

History of comorbidities

     

Hypertension b

2137 (26.0%)

920 (18.8%)

759 (31.4%)

458 (49.0%)

 < 0.001

Diabetes b

502 (6.1%)

180 (3.7%)

202 (8.4%)

120 (12.8%)

 < 0.001

Heart disease b

965 (11.7%)

471 (9.6%)

317 (13.1%)

177 (18.9%)

 < 0.001

Dyslipidemia b

792 (9.6%)

255 (5.2%)

323 (13.4%)

214 (22.9%)

 < 0.001

Kidney disease b

483 (5.9%)

286 (5.9%)

142 (5.9%)

55 (5.9%)

 > 0.999

History of medication use

     

Hypertension medications b

1597 (19.4%)

617 (12.6%)

603 (25.0%)

377 (40.3%)

 < 0.001

Diabetes medications b

323 (3.9%)

123 (2.5%)

111 (4.6%)

89 (9.5%)

 < 0.001

Dyslipidemia medications b

410 (5.0%)

118 (2.4%)

170 (7.0%)

122 (13.0%)

 < 0.001

SBP, mmHg

129.30 ± 21.25

126.75 ± 21.07

131.72 ± 20.78

136.39 ± 21.08

 < 0.001

DBP, mmHg

75.19 ± 12.10

73.08 ± 11.69

77.41 ± 11.85

80.49 ± 12.22

 < 0.001

TC, mg/dl

194.59 ± 38.77

191.31 ± 37.93

198.60 ± 39.05

201.38 ± 40.56

 < 0.001

HDL-C, mg/dl

51.50 ± 15.28

54.92 ± 15.73

47.55 ± 13.30

43.91 ± 12.13

 < 0.001

LDL-C, mg/dl b

117.67 ± 34.88

114.89 ± 33.91

121.79 ± 34.99

121.58 ± 38.02

 < 0.001

HbA1c, % b

5.29 ± 0.82

5.22 ± 0.76

5.36 ± 0.89

5.50 ± 0.91

 < 0.001

Median hsCRP (IQR), mg/l

1.03 (0.55, 2.18)

0.85 (0.49, 1.89)

1.18 (0.64, 2.23)

1.64 (0.89, 3.35)

 < 0.001

eGFR, ml/min/1.73m2 b

76.86 ± 42.82

76.33 ± 47.03

77.52 ± 35.23

77.94 ± 37.20

0.384

FBG, mg/dl

110.02 ± 35.82

107.12 ± 34.24

113.19 ± 37.92

116.98 ± 36.69

 < 0.001

Median TG (IQR), mg/dl

104.43 (74.34, 150.45)

92.04 (67.48, 130.98)

118.59 (84.96, 173.24)

142.49 (100.00, 203.55)

 < 0.001

TyG

8.67 ± 0.66

8.53 ± 0.60

8.83 ± 0.67

9.03 ± 0.70

 < 0.001

TyG-BMI c

204.22 ± 40.50

179.32 ± 22.76

227.28 ± 20.96

274.66 ± 32.05

 < 0.001

  1. Data are presented as mean ± SD or n(%), unless otherwise specified
  2. BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration ratio; FBG, fasting blood glucose; HbA1c, glycated hemoglobin; HDL-C, high-density lipoprotein cholesterol; IQR, interquartile range; LDL-C, low-density lipoprotein cholesterol; SD, standard deviation; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; TyG, triglyceride-glucose
  3. a P value was based on χ2 or analysis of variance or Kruskal–Wallis rank sum test where appropriate
  4. b Missing data: 22 for smoking status, 4 for drinking status, 43 for hypertension, 82 for diabetes, 33 for heart disease, 174 for dyslipidaemia, 43 for kidney disease, 44 for history of medication use for hypertension, 83 for history of medication use for diabetes, 178 for history of medication use for dyslipidaemia, 80 for SBP, 81 for DBP, 16 for LDL-C, 63 for HbA1c, 3 for eGFR
  5. c The TyG-BMI was calculated by the formula ln[TC (mg/dl) × FBG (mg/dl) / 2] × BMI (kg/m2)
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Cardiovascular Diabetology

ISSN: 1475-2840