Glycemic control and cardiovascular outcomes in patients with diabetes and coronary artery disease according to triglyceride-glucose index: a large-scale cohort study

Table 5 Glycemic control in relation to study endpoints according to TyG index tertiles

TyG tertiles	Glycemic control Events (%)		Univariable analysis		Multivariable analysis^c
TyG tertiles	Controlled	Uncontrolled	HR (95%CI)	P value	HR (95%CI)	P value
CV events^a
TyG T1	59 (3.0)	53 (3.9)	0.77 (0.53–1.12)	0.167	0.79 (0.53–1.16)	0.224
TyG T2	45 (3.0)	76 (4.1)	0.72 (0.50–1.04)	0.083	0.84 (0.56–1.25)	0.382
TyG T3	29 (3.1)	119 (5.0)	0.61 (0.40–0.91)	0.016	0.64 (0.42–0.96)	0.033
MACEs^b
TyG T1	47 (2.4)	47 (3.4)	0.69 (0.46–1.03)	0.072	0.70 (0.46–1.07)	0.101
TyG T2	40 (2.7)	64 (3.5)	0.76 (0.51–1.13)	0.182	0.90 (0.59–1.39)	0.639
TyG T3	24 (2.5)	106 (4.4)	0.56 (0.36–0.88)	0.011	0.61 (0.39–0.96)	0.034

^aCV events were defined as a composite of CV death, nonfatal MI and nonfatal stroke
^bMACEs were defined as a composite of CV death and nonfatal MI
^cModels adjusted for age, male sex, BMI, ACS presentation, family history of CAD, previous MI, previous revascularization, hypertension, previous stroke, PAD, current smoker, LVEF, serum creatinine, TC, HDL-C, LDL-C, hsCRP, SYNTAX score, CTO lesion, aspirin use, statins use and insulin use
Abbreviations as in Tables 1 and 3

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