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Table 2 Baseline characteristics according to TyG tertiles

From: Glycemic control and cardiovascular outcomes in patients with diabetes and coronary artery disease according to triglyceride-glucose index: a large-scale cohort study

Characteristicsa

TyG index tertiles

P value

T1 < 8.895

N = 3329

T2 [8.895, 9.400)

N = 3333

T3 ≥ 9.400

N = 3334

TyG index

8.54 ± 0.28

9.14 ± 0.14

9.88 ± 0.42

< 0.001

Age, years

61.66 ± 9.03

60.41 ± 8.99

58.82 ± 9.54

< 0.001

Male

2597 (78.0)

2511 (75.3)

2394 (71.8)

< 0.001

BMI

25.72 ± 3.19

26.44 ± 3.14

26.76 ± 3.23

< 0.001

Clinical presentation

   

< 0.001

 CCS

1345 (40.4)

1263 (37.9)

1182 (35.5)

 

 ACS

1984 (59.6)

2070 (62.1)

2152 (64.5)

 

Family history of CAD

367 (11.0)

403 (12.1)

402 (12.1)

0.306

Prior MI

847 (25.4)

865 (26.0)

911 (27.3)

0.196

Prior revascularizationb

1044 (31.4)

972 (29.2)

1031 (30.9)

0.119

Hypertension

2261 (67.9)

2337 (70.1)

2347 (70.4)

0.055

Prior stroke

519 (15.6)

500 (15.0)

478 (14.3)

0.358

PAD

304 (9.1)

245 (7.4)

194 (5.8)

< 0.001

Current smoker

901 (27.1)

1018 (30.5)

1134 (34.0)

< 0.001

CKD

49 (1.5)

74 (2.2)

106 (3.2)

< 0.001

LVEF, %

61.78 (6.79)

61.47 (6.81)

61.47 (6.95)

0.108

Laboratory tests

    

Serum creatinine, µmol/L

81.68 ± 16.75

82.67 ± 17.77

84.33 ± 19.60

< 0.001

eGFR, ml/min/m2

86.45 ± 17.04

85.42 ± 18.60

83.93 ± 20.11

< 0.001

HbA1c, %

6.99 ± 1.05

7.32 ± 1.17

7.91 ± 1.45

< 0.001

FBG, mmol/L

6.53 ± 1.41

7.79 ± 1.90

10.03 ± 3.40

< 0.001

TG, mmol/L

1.04 ± 0.28

1.59 ± 0.39

2.85 ± 1.64

< 0.001

TC, mmol/L

3.57 ± 0.86

3.96 ± 0.98

4.46 ± 1.16

< 0.001

HDL-C, mmol/L

1.15 ± 0.31

1.07 ± 0.27

1.00 ± 0.24

< 0.001

LDL-C, mmol/L

2.11 ± 0.74

2.43 ± 0.87

2.61 ± 1.00

< 0.001

hsCRP, mg/L

2.35 ± 2.90

2.66 ± 3.01

2.98 ± 3.14

< 0.001

Angiographic data

    

SYNTAX score

12.54 ± 5.23

12.88 ± 5.64

12.71 ± 5.53

0.035

Left main disease

301 (9.0)

290 (8.7)

258 (7.7)

0.141

Three-vessel disease

1583 (47.6)

1593 (47.8)

1589 (47.7)

0.98

CTO lesion

313 (9.4)

378 (11.3)

365 (10.9)

0.025

Thrombotic lesion

45 (1.4)

65 (2.0)

92 (2.8)

< 0.001

Ostial lesion

400 (12.0)

418 (12.5)

387 (11.6)

0.502

Type B2/C lesion

2464 (74.0)

2493 (74.8)

2503 (75.1)

0.588

Severe calcification

143 (4.3)

107 (3.2)

109 (3.3)

0.028

Medications

    

Aspirin

2505 (75.2)

2501 (75.0)

2345 (70.3)

< 0.001

Statins

3215 (96.6)

3234 (97.0)

3239 (97.2)

0.359

ACEI/ARB

919 (27.6)

968 (29.0)

954 (28.6)

0.41

β-blocker

2913 (87.5)

2974 (89.2)

3094 (92.8)

< 0.001

Diabetic therapy

    

 Diet control

337 (10.1)

304 (9.1)

251 (7.5)

0.001

 Oral medication

1741 (52.3)

1626 (48.8)

1714 (51.4)

0.012

 Insulin use

526 (15.8)

541 (16.2)

689 (20.7)

< 0.001

  1. aValues are expressed as mean ± standard deviation and count (percentage)
  2. bRevascularization included percutaneous coronary intervention and coronary artery bypass grafting
  3. Abbreviations as in Table 1
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Cardiovascular Diabetology

ISSN: 1475-2840