Fig. 2

ASGR1 deficiency does not alter glucose homeostasis but reduces plasma lipid levels. A Glucose tolerance test (GTT) B Area under the curve (AUC) in male wildtype (WT) and ASGR1^−/− mice after 20 weeks of HFD. C Insulin tolerance test (ITT) D and related AUC in male wildtype (WT) and ASGR1^−/− mice after 20 weeks of HFD. E Total plasma cholesterol in male WT and ASGR1^−/− mice after 20 weeks of HFD. F Cholesterol content in plasma lipoprotein fractions of male WT and ASGR1^−/− mice after 20 weeks of HFD. G Triglycerides concentration in the plasma of male WT and ASGR1^−/− mice after 20 weeks of HFD. H Triglyceride content in plasma lipoprotein fractions of male WT and ASGR1^−/− mice after 20 weeks of HFD. Data are obtained from three independent experimental groups. Each bar and error represent the mean ± SEM. *p < 0.05, **p < 0.01 and ***p < 0.001