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Table 2 Association of baseline, variability, cumulative of TyG index with the incidence of CKD

From: Association of long-term triglyceride-glucose index patterns with the incidence of chronic kidney disease among non-diabetic population: evidence from a functional community cohort

 

Model 1

 

Model 2

 

Model 3

  
 

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

 

Baseline TyG index

      

Q1

-

 

-

 

-

  

Q2

1.246 (1.009, 1.538)

0.041

1.172 (0.937, 1.465)

0.164

-

  

Q3

1.384 (1.125, 1.702)

0.002

1.303 (1.034, 1.642)

0.025

-

  

Q4

1.811 (1.486, 2.206)

< 0.001

1.572 (1.227, 2.015)

< 0.001

-

  

P for trend

 

< 0.001

 

< 0.001

   

TyG index variability

      

Q1

-

   

-

  

Q2

1.199 (0.976, 1.474)

0.084

1.177 (0.951, 1.456)

0.134

1.179 (0.953, 1.459)

0.129

 

Q3

1.537 (1.264, 1.869)

< 0.001

1.491 (1.219, 1.822)

< 0.001

1.488 (1.217, 1.819)

< 0.001

 

Q4

1.757 (1.447, 2.135)

< 0.001

1.772 (1.453, 2.162)

< 0.001

1.714 (1.403, 2.094)

< 0.001

 

P for trend

 

< 0.001

 

< 0.001

 

< 0.001

 

Cumulative TyG index

      

Q1

-

   

-

  

Q2

1.195 (0.953, 1.498)

0.122

1.144 (0.906, 1.445)

0.258

1.138 (0.899, 1.442)

0.282

 

Q3

1.732 (1.400, 2.142)

< 0.001

1.634 (1.299, 2.056)

< 0.001

1.617 (1.268, 2.061)

< 0.001

 

Q4

2.206 (1.795, 2.711)

< 0.001

2.091 (1.646, 2.655)

< 0.001

2.049 (1.549, 2.711)

< 0.001

 

P for trend

 

< 0.001

 

< 0.001

 

< 0.001

 
  1. CKD: chronic kidney disease, TyG index: triglyceride glucose index
  2. Model 1 was adjusted for age and sex
  3. Model 2 was additionally adjusted for current smoking, current drinking, educational level, physical activity, hypertension, BMI, LDL-C, HDL-C, ALT, AST, Cr, UA, Urea and baseline eGFR
  4. Model 3 was additionally adjusted for baseline TyG index
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Cardiovascular Diabetology

ISSN: 1475-2840