Fig. 2

HOMA-IR categories, and association with the multiterritorial extent of subclinical atherosclerosis in different vascular territories. (A) Multiterritorial extent of subclinical atherosclerosis (SA), assessed by 2-dimensional vascular ultrasound and non-contrast coronary computed tomography, stratified by HOMA-IR category. Multiterritorial SA extent for this figure is defined by combining data from both imaging techniques to classify individuals as having no disease (0 vascular sites affected) or having focal (1 site), intermediate (2 to 3 sites), or generalized atherosclerosis (4 to 6 sites). (B–D) Presence of SA in different vascular territories stratified by HOMA-IR category. *Indicates statistically significant differences (p < 0.025) as compared to the lowest HOMA-IR category (HOMA-IR < 2, reference group). HOMA-IR = homeostatic model assessment of insulin resistance