Table 4 Multivariable Cox regression analysis of differences in MACE between individuals with NGR and prediabetes

NGR without progress

15,524

359

0.67

53,533.18

Ref.

Ref.

NFR with progress

3,672

160

1.06

15,101.72

1.67

1.39

2.02

< 0.001

1.54

1.27

1.88

< 0.001

Prediabetes without progress

14,834

596

1.16

51,181.16

1.74

1.53

1.98

< 0.001

1.37

1.19

1.59

< 0.001

Prediabetes with progress

2,920

161

1.35

11,966.73

2.13

1.77

2.56

< 0.001

1.86

1.52

2.28

< 0.001

Prediabetes Overall

17,754

757

1.20

63,147.89

1.81

1.60

2.05

< 0.001

1.46

1.27

1.67

< 0.001

 - HbA1c 3.5-5.0%

41

1

0.82

122.01

1.14

0.16

8.10

0.898

0.79

0.11

5.60

0.810

 - HbA1c 5.0-5.5%

329

13

1.33

975.63

1.88

1.08

3.28

0.025

1.52

0.87

2.66

0.138

 - HbA1c 5.5-6.0%

4,346

217

1.42

15,250.41

2.14

1.81

2.54

< 0.001

1.67

1.39

2.01

< 0.001

 - HbA1c 6.0-6.5%

4,001

262

1.79

14,626.20

2.74

2.33

3.21

< 0.001

2.10

1.76

2.51

< 0.001

 - IFG or IGT

9,037

264

0.82

32,173.64

1.24

1.06

1.45

0.008

1.06

0.89

1.26

0.499

 - IFG and IGT

120

5

1.04

481.32

1.64

0.68

3.96

0.274

1.42

0.53

3.83

0.484

 - isolated IFG

8,971

259

0.81

31,963.71

1.22

1.04

1.44

0.014

1.05

0.89

1.25

0.565

 - isolated IGT

186

10

1.45

691.25

2.23

1.19

4.18

0.012

1.72

0.85

3.48

0.130