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Table 3 Multivariable Cox regression analysis of differences in MALE between individuals with NGR and prediabetes

From: Prediabetes increases the risk of major limb and cardiovascular events

 

N

Event no.

Incidence rate (%)

Incidence (person-year)

Model 1

Model 2

HR

95% C.I.

p value

HR

95% C.I.

p value

lower

upper

lower

upper

NGR without progress

15,524

490

0.93

52,726.57

Ref.

   

Ref.

   

NGR with progress

3,672

156

1.04

15,030.08

1.20

1.00

1.43

0.053

1.45

1.19

1.77

< 0.001

Prediabetes without progress

14,834

545

1.07

50,825.41

1.16

1.02

1.31

0.020

1.23

1.06

1.42

0.007

Prediabetes with progress

2,920

133

1.12

11,925.41

1.28

1.06

1.56

0.011

1.43

1.15

1.77

0.001

Prediabetes Overall

17,754

678

1.08

62,750.82

1.18

1.05

1.32

0.006

1.26

1.10

1.46

0.001

 - HbA1c 3.5-5.0%

41

0

0.00

122.03

-

   

-

   

 - HbA1c 5.0-5.5%

329

14

1.46

959.59

1.46

0.86

2.49

0.160

1.78

1.04

3.04

0.036

 - HbA1c 5.5-6.0%

4,346

157

1.03

15,271.34

1.12

0.93

1.34

0.223

1.29

1.06

1.58

0.012

 - HbA1c 6.0-6.5%

4,001

165

1.12

14,737.09

1.24

1.04

1.48

0.002

1.39

1.14

1.70

< 0.001

 - IFG or IGT

9,037

342

1.08

31,660.76

1.17

1.02

1.35

0.023

1.18

1.00

1.39

0.053

 - IFG and IGT

120

3

0.62

482.82

0.71

0.23

2.21

0.553

1.02

0.33

3.17

0.978

 - isolated IFG

8,971

340

1.08

31,447.77

1.18

1.02

1.35

0.022

1.18

1.00

1.39

0.054

 - isolated IGT

186

5

0.72

695.80

0.80

0.33

1.93

0.620

1.07

0.44

2.60

0.875

  1. * NGR without progress as reference
  2. * Model 1: Crude; Model 2: Adjust age, sex, BMI, hypertension, hyperlipidemia, HF, gout, CAD, AF, eGFR