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Table 2 Cumulative incidence and incidence rates of major adverse limb events (MALE) and major adverse cardiovascular events (MACE).

From: Prediabetes increases the risk of major limb and cardiovascular events

  

N

Event

Incidence (%)

Age standardized incidence (%)

Incidence rate (per 1000 person-year)

Time at risk (person-year)

Median follow-up time (month)

Incidence rate ratio (IRR) and 95%CI

MALE

 

NGR

Overall

19,196

646

3.37

2.86

9.53

67,756.65

46.43

0.95 (0.87–1.05)

 

NGR with progress

3,672

156

4.25

3.46

10.38

15,030.08

56.17

1.04 (0.96–1.12)

 

NGR without progress

15,524

490

3.16

2.71

9.29

52,726.57

43.97

0.93 (0.80–1.07)

Prediabetes

Overall

17,754

678

3.82

3.22

10.80

62,750.82

46.37

1.08 (0.93–1.26)

 

Prediabetes with progress

2,920

133

4.55

3.69

11.15

11,925.41

57.35

1.12 (0.90–1.38)

 

Prediabetes without progress

14,834

545

3.67

3.15

10.72

50,825.41

44.03

1.07 (0.94–1.23)

MACE

 

NGR

Overall

19,196

519

2.70

2.27

7.56

68,634.90

47.10

0.76 (0.44–1.31)

 

NGR with progress

3,672

160

4.36

3.68

10.59

15,101.72

56.60

1.06 (0.95–1.19)

 

NGR without progress

15,524

359

2.31

1.90

6.71

53,533.18

44.57

0.67 (0.31–1.47)

Prediabetes

Overall

17,754

757

4.26

3.76

11.99

63,147.89

46.80

1.20 (0.84–1.71)

 

Prediabetes with progress

2,920

161

5.51

4.92

13.45

11,966.73

57.67

1.35 (0.75–2.41)

 

Prediabetes without progress

14,834

596

4.02

3.53

11.64

51,181.16

44.47

1.16 (0.86–1.57)

  1. * NGR, normal glucose regulation