Table 1 Patients’ demographics
From: Prediabetes increases the risk of major limb and cardiovascular events
| Â | NGR | Prediabetes | p value (normal vs. prediabetes) | ||||
|---|---|---|---|---|---|---|---|
Overall N = 19,196 | NGR with progress N = 3,672 | NGR without progress N = 15,524 | Overall N = 17,754 | Prediabetes with progress N = 2,920 | Prediabetes without progress N = 14,834 | ||
Age, yr | 62.9 ± 10.4 | 64.0 ± 10.4 | 62.7 ± 10.4 | 65.2 ± 10.2 | 64.8 ± 9.9 | 65.2 ± 10.2 | < 0.001 |
Male | 7,821 (40.7) | 1,702 (46.4) | 6,119 (39.4) | 8,675 (48.9) | 1,489 (51.0) | 7,186 (48.4) | < 0.001 |
BMI, kg/m2 | 23.6 ± 3.8 | 24.52 ± 4.0 | 23.4 ± 3.7 | 25.1 ± 4.1 | 25.9 ± 4.3 | 24.9 ± 4.0 | < 0.001 |
History of hypertension | 4,076 (21.2) | 1,107 (30.2) | 2,969 (19.1) | 4,902 (27.6) | 993 (34.0) | 3,909 (26.4) | < 0.001 |
History of hyperlipidemia | 2,806 (14.6) | 893 (24.3) | 1,913 (12.3) | 3,421 (19.3) | 744 (25.5) | 2,677 (18.1) | < 0.001 |
History of HF | 104 (0.5) | 25 (0.7) | 79 (0.5) | 128 (0.7) | 17 (0.6) | 111 (0.8) | 0.029 |
History of CAD | 1,663 (8.7) | 523 (14.2) | 1,140 (7.3) | 2,290 (12.9) | 458 (15.7) | 1,832 (12.4) | < 0.001 |
History of CKD | 359 (1.9) | 77 (2.1) | 282 (1.8) | 296 (1.7) | 40 (1.4) | 256 (1.7) | 0.140 |
History of Gout | 198 (1.0) | 31 (0.8) | 167 (1.1) | 235 (1.3) | 33 (1.1) | 202 (1.4) | 0.009 |
History of COPD | 582 (3.0) | 116 (3.2) | 466 (3.0) | 622 (3.5) | 108 (3.7) | 514 (3.5) | 0.011 |
History of AF | 530 (2.8) | 22 (0.6) | 508 (3.3) | 663 (3.7) | 19 (0.7) | 644 (4.3) | < 0.001 |
Baseline HbA1C, % | 5.4 ± 0.2 | 5.4 ± 0.2 | 5.4 ± 0.2 | 5.9 ± 0.3 | 6.1 ± 0.3 | 5.9 ± 0.3 | < 0.001 |
Baseline FG, mmol/L | 90.1 ± 7.1 | 91.7 ± 7.3 | 89.7 ± 7.1 | 105.9 ± 9.4 | 110.5 ± 9.1 | 105.0 ± 9.2 | < 0.001 |
eGFR, mL / min / 1.73m2 | 75.2 ± 26.2 | 75.1 ± 27.6 | 75.3 ± 25.9 | 75.0 ± 27.2 | 77.4 ± 29.3 | 74.5 ± 26.7 | 0.494 |
TG, mg/dL | 121.7 ± 82.6 | 138.8 ± 96.1 | 116.9 ± 77.7 | 141.8 ± 96.4 | 157.9 ± 115.3 | 138.0 ± 91.0 | < 0.001 |
TCHO, mg/dL | 189.1 ± 40.2 | 185.9 ± 42.7 | 189.9 ± 39.5 | 186.1 ± 41.9 | 182.2 ± 42.8 | 187.0 ± 41.7 | < 0.001 |
LDL, mg/dL | 113.1 ± 32.5 | 112.7 ± 34.0 | 113.2 ± 32.0 | 112.1 ± 33.9 | 110.5 ± 34.8 | 112.5 ± 33.7 | 0.294 |
HDL, mg/dL | 53.6 ± 14.7 | 49.7 ± 13.9 | 54.9 ± 14.7 | 49.1 ± 13.4 | 45.9 ± 11.9 | 49.9 ± 13.6 | < 0.001 |
NT-proBNP, pg/ mL | 3364.0 ± 8082.0 | 3652.5 ± 8514.1 | 3208.0 ± 7839.4 | 2477.0 ± 6377.9 | 3149.5 ± 7818.7 | 2291.3 ± 5908.7 | 0.177 |