From: Triglyceride-glucose index is associated with a higher risk of stroke in a hypertensive population
TyG index | N | Events (%) | Crude model | Adjusted model* | ||
---|---|---|---|---|---|---|
HR (95%CI) | P | HR (95%CI) | P | |||
Total stroke | ||||||
Continuous | 7569 | 288 (3.8) | 1.30 (1.07, 1.59) | 0.009 | 1.41 (1.14, 1.75) | 0.002 |
Quartiles | ||||||
Q1 (< 8.5) | 1892 | 63 (3.3) | ref | ref | ||
Q2 (8.5–8.8) | 1890 | 58 (3.1) | 0.93 (0.65, 1.33) | 0.692 | 1.04 (0.72, 1.51) | 0.822 |
Q3 (8.8–9.2) | 1893 | 87 (4.6) | 1.39 (1.00, 1.92) | 0.047 | 1.43 (1.02, 2.02) | 0.039 |
Q4 (≥ 9.2) | 1894 | 80 (4.2) | 1.27 (0.92, 1.77) | 0.151 | 1.45 (1.01, 2.08) | 0.042 |
P for trend | 0.035 | 0.013 | ||||
Categories | ||||||
Q1–Q2 (< 8.8) | 3782 | 121 (3.2) | ref | ref | ||
Q3–Q4 (≥ 8.8) | 3787 | 167 (4.4) | 1.38 (1.09,1.74) | 0.007 | 1.41(1.10,1.81) | 0.007 |
P for trend | 0.007 | 0.007 | ||||
Ischemic stroke | ||||||
Continuous | 7530 | 248 (3.3) | 1.53 (1.24, 1.88) | < 0.001 | 1.66(1.33, 2.09) | < 0.001 |
Quartiles | ||||||
Q1 (< 8.5) | 1882 | 43 (2.3) | ref | ref | ||
Q2 (8.5–8.8) | 1883 | 51 (2.7) | 1.20 (0.80, 1.80) | 0.376 | 1.37(0.90, 2.08) | 0.141 |
Q3 (8.8–9.2) | 1883 | 79 (4.2) | 1.86 (1.28, 2.69) | 0.001 | 1.98(1.34, 2.93) | < 0.001 |
Q4 (≥ 9.2) | 1882 | 75 (4.0) | 1.76 (1.21, 2.56) | 0.003 | 2.06(1.37, 3.09) | < 0.001 |
P for trend | < 0.001 | < 0.001 | ||||
Categories | ||||||
Q1–Q2 (< 8.8) | 3765 | 94 (2.5) | ref | ref | ||
Q3–Q4 (≥ 8.8) | 3765 | 154 (4.1) | 1.64 (1.27, 2.12) | < 0.001 | 1.70 (1.29, 2.24) | < 0.001 |
P for trend | < 0.001 | < 0.001 |