Table 1 Baseline characteristics of the study participants
|  | Total (n = 82,172) | HsCRP < 2 mg/L (n = 60,846) | HsCRP ≥ 2 mg/L (n = 21,326) | P-difference |
|---|---|---|---|---|
Age, mean (SD), years | 50.4 ± 12.0 | 49.4 ± 11.8 | 53.2 ± 12.2 |  < 0.0001 |
Male, No. (%) | 66,047 (80.4) | 49,241 (80.9) | 16,806 (78.8) |  < 0.0001 |
BMI, mean (SD), kg/m2 | 25.0 ± 3.4 | 24.7 ± 3.3 | 25.6 ± 3.7 |  < 0.0001 |
BMI-categories, No. (%) |  |  |  |  < 0.0001 |
  Underweight/normal weight | 33,220 (40.4) | 25,937 (42.6) | 7283 (34.1) |  |
  Overweight | 34,273 (41.7) | 25,283 (41.6) | 8990 (42.2) |  |
  Obese | 14,679 (17.9) | 9626 (15.8) | 5053 (23.7) |  |
Waist circumference, mean (SD), cm | 86.6 ± 9.7 | 85.6 ± 9.4 | 89.3 ± 10.1 |  < 0.0001 |
Waist circumference-categories, No. (%) |  |  |  |  < 0.0001 |
  Non abdominal obesity | 48,935 (59.6) | 38,859 (63.9) | 10,076 (47.3) |  |
  Abdominal obesity | 33,237 (40.4) | 21,987 (36.1) | 11,250 (52.8) |  |
Fatty liver degrees, No. (%) |  |  |  |  < 0.0001 |
  No fatty liver | 57,611 (70.1) | 44,386 (73.0) | 13,225 (62.0) |  |
  Gentle fatty liver | 16,548 (20.1) | 11,378 (18.7) | 5170 (24.2) |  |
  Moderate and severe fatty liver | 8013 (9.8) | 5082 (8.3) | 2931 (13.7) |  |
hsCRP, median (IQR), mg/L | 0.8 (0.3–2.1) | 0.5 (0.2–0.9) | 4.5 (2.8–7.8) |  < 0.0001 |
SBP, mean (SD), mm Hg | 129.7 ± 20.4 | 128.7 ± 20.0 | 132.4 ± 21.5 |  < 0.0001 |
DBP, median (IQR), mm Hg | 80.0 (78.0–90.0) | 80.0 (76.7–90.0) | 80.7 (79.3–90.0) |  < 0.0001 |
HDL-C, median (IQR), mmol/L | 1.50 (1.28–1.76) | 1.51 (1.28–1.77) | 1.49 (1.27–1.75) | 0.1001 |
TC, mean (SD), mmol/L | 4.9 ± 1.1 | 4.9 ± 1.1 | 4.9 ± 1.1 | 0.0024 |
TG, median (IQR), mmol/L | 1.25 (0.88–1.88) | 1.22 (0.87–1.83) | 1.31(0.92–2.00) |  < 0.0001 |
Family history of diabetes, No. (%) | 6823 (8.3) | 5230 (8.6) | 1593 (7.5) |  < 0.0001 |
Education, No. (%) |  |  |  |  < 0.0001 |
  Less than high school | 64,993 (79.1) | 47,916 (78.8) | 17,077 (80.1) |  |
  High school and above | 17,179 (20.9) | 12,930 (21.2) | 4249 (19.9) |  |
Current drinker, No. (%) | 31,327 (38.1) | 24,134 (39.7) | 7193 (33.7) |  < 0.0001 |
Smoking habits, No. (%) |  |  |  |  < 0.0001 |
  Never smoker | 49,046 (59.7) | 37,210 (61.2) | 11,836 (55.6) |  |
  Ever smoker | 4457 (5.4) | 3170 (5.2) | 1287 (6.0) |  |
  Current smoker | 28,669 (34.9) | 20,466 (33.6) | 8203 (38.4) |  |
Physical activities, No. (%) |  |  |  |  < 0.0001 |
  Low | 7433 (9.0) | 5687 (9.4) | 1746 (8.2) |  |
  Moderate | 62,122 (75.6) | 45,794 (75.2) | 16,328 (76.5) |  |
  High | 12,617 (15.4) | 9365 (15.4) | 3252 (15.3) |  |
CVD, No. (%) | 2458 (3.0) | 1588 (2.6) | 870 (4.1) |  < 0.0001 |
Medication use, No. (%) | Â | Â | Â | Â |
  Antihypertensives | 2238 (2.7) | 1426 (2.3) | 812 (3.8) |  < 0.0001 |
  Statin | 175 (0.2) | 117 (0.2) | 58 (0.3) |  < 0.0001 |
  Fibrate | 64 (0.08) | 38 (0.06) | 26 (0.12) | 0.0299 |