Plaque volume and plaque risk profile in diabetic vs. non-diabetic patients undergoing lipid-lowering therapy: a study based on 3D intravascular ultrasound and virtual histology

Table 2 IVUS analysis of plaque morphology expressed as mean values per 5 mm vessel segments

	DM (17 pts, 192 segments)	Non-DM (44 pts, 506 segments)	p
Lumen area BL (mm²)	8.53 ± 3.8	9.27 ± 3.89	0.44
Lumen area FU (mm²)	8.54 ± 3.81	9.19 ± 3.79	0.53
Δ Lumen area (mm²)	0.02 ± 1.1	− 0.08 ± 1.2	0.54
p value for change between BL and FU	0.96	0.64
Vessel area BL (mm²)	15.79 ± 5.67	16.66 ± 5.62	0.5
Vessel area FU (mm²)	16.01 ± 5.7	16.1 ± 5.37	0.94
Δ Vessel area (mm²)	0.22 ± 1.4	− 0.56 ± 1.8	0.04
p value for change between BL and FU	0.54	0.01
Plaque area BL (mm²)	7.26 ± 2.99	7.39 ± 3.31	0.7
Plaque area FU (mm²)	7.47 ± 3.08	6.91 ± 3.08	0.42
Δ Plaque area (mm²)	0.21 ± 0.97	− 0.47 ± 1.15	0.001
p value for change between BL and FU	0.34	0.001
Plaque atheroma volume BL	45.7 ± 5.0%	44.6 ± 8.0%	0.60
Plaque atheroma volume FU	46.4 ± 4.2%	43.2 ± 7.8%	0.14
Δ Plaque atheroma volume	0.7 ± 2.8%	− 1.4 ± 2.5%	0.007
p value for change between BL and FU	0.56	0.4

ISSN: 1475-2840