Table 3 General characteristics of patients by tertiles of circulating sortilin level
Tertiles of circulating sortilin levels | P value | |||
|---|---|---|---|---|
Tertile 1 (<1.17 ng/ml) n = 49 | Tertile 2 (1.17–1.59 ng/ml) n = 49 | Tertile 3 (≥1.60 ng/ml) n = 49 | ||
Age (years) | 50.4 ± 6.5a | 60.0 ± 9.9b | 56.2 ± 13.4b | <0.001 |
Men (%) | 73.5 | 67.3 | 67.3 | 0.750 |
Body weight (kg) | 67.4 ± 10.2 | 64.2 ± 11.1 | 64.2 ± 11.5 | 0.249 |
BMI (kg/m2) | 24.1 ± 2.3 | 23.9 ± 3.1 | 23.8 ± 3.0 | 0.890 |
SBP (mmHg) | 119.9 ± 16.3 | 122.8 ± 15.9 | 124.0 ± 18.8 | 0.473 |
DBP (mmHg) | 73.8 ± 11.7 | 73.9 ± 10.5 | 73.5 ± 12.9 | 0.985 |
Glucose (mg/dl) | 94.0 ± 1.3a | 113.3 ± 1.4b | 115.1 ± 1.5b | 0.003 |
HbA1c (%) | 5.9 ± 1.1a | 6.3 ± 1.2a | 6.6 ± 1.3b | 0.011 |
TC (mg/dl) | 202.2 ± 34.9 | 191.7 ± 41.5 | 188.2 ± 43.5 | 0.206 |
LDL-C (mg/dl) | 111.1 ± 22.5 | 109.9 ± 25.3 | 109.3 ± 32.3 | 0.946 |
HDL-C (mg/dl) | 51.5 ± 13.7 | 49.7 ± 10.9 | 46.1 ± 11.9 | 0.082 |
TG (mg/dl) | 122.0 ± 1.6 | 110.8 ± 1.7 | 118.9 ± 1.7 | 0.631 |
hs-CRP (mg/dl) | 0.10 ± 0.15 | 0.28 ± 0.56 | 0.49 ± 1.09 | 0.015 |
DM (%) | 8.2 | 34.7 | 44.9 | <0.001 |
CAD (%) | 0 | 26.5 | 36.7 | <0.001 |
HTN (%) | 14.3 | 75.5 | 71.4 | <0.001 |
Dyslipidemia (%) | 30.6 | 32.7 | 49.0 | 0.120 |