Fig. 2
Mdivi-1 inhibited Drp1 translocation to the mitochondria and prevented mitochondrial fission following MI/R in diabetic mice. a Total Drp1 expression. b Mitochondrial Drp1 expression. c Number of mitochondria per μm2 in each field of view. d Representative transmission electron microscopic images (major finding is c, e). e Percentage of mitochondria that sorted into three size categories based on area. MI/R group means diabetic mice subjected to MI/R and vehicle (dimethyl sulfoxide) administration. Values are mean ± SEM. N = 3–6 hearts for each group. *P < 0.05, **P < 0.01 vs. Sham. # P < 0.05, ## P < 0.01 vs. MI/R