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Table 1 Baseline characteristics in patients with or without diabetes

From: Diabetes does not impact the diagnostic performance of contrast-based fractional flow reserve: insights from the CONTRAST study

 

No diabetes (N = 544)

Diabetes (N = 219)

p value

Age (years)

65.4 ± 9.7

66.4 ± 9.7

0.24

Male

74.8% (407)

63.9% (140)

0.003

BMI (kg/m2)

26.8 ± 4.5

28.6 ± 5.0

<0.0001

Smoking (current or past)

47.8% (260)

47.0% (103)

0.85

Hypertension

67.5% (367)

81.3% (178)

<0.0001

Dyslipidemia

61.4% (334)

79.5% (174)

<0.0001

Family history of CAD

26.1% (142)

22.4% (49)

0.28

Renal dysfunction (eGFR < 60 ml/min)

8.6% (47)

12.3% (27)

0.12

Prior MI

24.1% (131)

30.6% (67)

0.06

Prior PCI

14.0% (76)

17.4% (38)

0.24

Peripheral vascular disease

3.7% (20)

6.4% (14)

0.10

Clinical presentation

  

0.37

 Stable

79.2% (431)

76.3% (167)

 

 ACS

20.8% (113)

23.7% (52)

 

 Unstable Angina

9.2% (50)

15.5% (34)

 

 NSTEMI

10.7% (58)

6.8% (15)

 

 STEMI

0.9% (5)

1.4% (3)

 

Coronary vessel

  

0.86

 Left main

3.1% (17)

3.7% (8)

 

 LAD

60.7% (330)

59.4% (130)

 

 LCx

17.5% (95)

19.6% (43)

 

 RCA

18.8% (102)

17.4% (38)

 

Contrast medium

  

0.03

 Iobitridol

5.3% (29)

5.0% (11)

 

 Iodixanol

24.3% (132)

26.0% (57)

 

 Iohexol

15.8% (86)

9.1% (20)

 

 Iomeprol

31.1% (169)

26.5% (58)

 

 Iopamidol

1.3% (7)

0.5% (1)

 

 Iopromide

7.9% (43)

11.9% (26)

 

 Ioversol

8.5% (46)

10.0% (22)

 

 Ioxaglate

5.9% (32)

11.0% (24)

 

Volume of IC contrast (ml)

7.9 ± 1.5

7.7 ± 1.6

0.03

 5

2.0% (11)

2.7% (6)

 

 6–7

39.7% (216)

49.3% (108)

 

 8–9

30.1% (164)

21.0% (46)

 

 10

27.9% (152)

26.9% (59)

 

 12

0.2% (1)

0% (0)

 

Dose of IC adenosine* (μg)

166.3 ± 46.1

171.2 ± 47.1

0.27

 <80

2.3% (9)

1.3% (2)

 

 80–90

7.1% (28)

7.1% (11)

 

 100–150

28.4% (112)

29.0% (45)

 

 160–200

48.5% (191)

45.2% (70)

 

 >200

13.7% (54)

17.4% (27)

 
  1. ACS acute coronary syndrome, BMI body mass index, CAD coronary artery disease, GFR glomerular filtration rate, IC intracoronary, LAD left anterior descending coronary artery, LCx left circumflex coronary artery, MI myocardial infarction, NSTEMI non ST-segment elevation MI, PCI percutaneous coronary intervention, RCA right coronary artery, STEMI ST-segment elevation MI
  2. * Only 549 of 763 patients received IC adenosine, while all other rows are based on 763 total