Association of metabolic syndrome and its components with arterial stiffness in Caucasian subjects of the MARK study: a cross-sectional trial

Table 4 Multiple logistic regression analysis of associations between MetS/components and baPWV and CAVI status in males and females

Components MetS	Global (n = 2351)		Males subjects (n = 1450)		Females subjects (n = 901)
	OR (95 % CI)	p value	OR (95 % CI)	p value	OR (95 % CI)	p value
Dependent variable: baPWV
High BP	6.899 (3.522 to 13.511)	<0.001	7.578 (2.975 to 19.345)	<0.001	5.272 (1.975 to 19.345)	<0.001
High FPG	1.527 (1.123 to 2.077)	0.007	1.290 (0.875 to 1.902)	0.199	2.035 (1.221 to 3.392)	0.006
High TGC	0.745 (0.559 to 0.992)	0.044	0.738 (0.480 to 1.135)	1.116	0.802 (0.534 to 1.205)	0.287
Low HDL-C	1.202 (0.915 to 1.579)	0.186	1.159 (0.811 to 1.656)	0.419	1.329 (0.863 to 2.248)	0.197
High WC	0.965 (0.743 to 1.254)	0.792	0.874 (0.633 to 1.207)	0.414	1.149 (0.675 to 1.953)	0.609
MetS	1.421 (1.062 to 1.902)	0.018	1.512 (1.032 to 2.215)	0.034	1.679 (1.019 to 2.765)	0.042
Dependent variable: CAVI
High BP	2.204 (1.629 to 2.983)	<0.001	2.238 (1.499 to 3.339)	<0.001	2.115 (1.320 to 3.338)	0.002
High FPG	1.368 (1.090 to 1.718)	0.007	1.401 (1.052 to 1.866)	0.021	1.256 (0.857 to 1.842)	0.242
High TGC	0.931 (0.755 to 1.147)	0.500	1.031 (0.768 to 1.384)	0.839	0.888 (0.651 to 1.213)	0.457
Low HDL-C	1.283 (1.043 to 1.579)	0.018	1.374 (1.054 to 1.792)	0.019	1.166 (0.832 to 1.633)	0.372
High WC	0.686 (0.565 to 0.834)	<0.001	0.786 (0.617 to 1.001)	0.051	0.741 (0.511 to 1.075)	0.115
MetS	1.543 (1.235 to 1.927)	<0.001	1.723 (1.286 to 2.307)	<0.001	1.424 (0.990 to 2.048)	0.056

Dependent variable: CAVI and baPWV (values of CAVI ≥9 and baPWV ≥17.5 m/s was considered abnormal)
Multiple logistic regression analysis was used to analyze the associations of MetS status and MetS components with baPWV and CAVI globally and stratified by gender. Age, height, weight, antihypertensive drugs, lipid-lowering drugs and antidiabetic drugs were adjusted in the regression models. The exception was WC, which was adjusted for age and drug use because of collinearity problems
MetS metabolic syndrome; baPWV brachial-ankle pulse wave velocity; CAVI cardio-ankle vascular index; OR odds ratio; CI confidence interval; BP blood pressure; FPG fasting plasma glucose; TGC triglycerides; HDL-C high density lipoprotein cholesterol; WC waist circumference

ISSN: 1475-2840