From: Common dysregulated pathways in obese adipose tissue and atherosclerosis
DPa | NESd | NOM p-Vale | FDRf | IRPg | MRPh | Name | ||||
---|---|---|---|---|---|---|---|---|---|---|
ATb | AOc | AT | AO | AT | AO | AT | AO | |||
x | x | 2.43 | 1.35 | <0.001 | 0.047 | 0.000 | 0.098 | Â | Â | E2F targets |
x | x | 2.39 | 1.74 | <0.001 | <0.001 | 0.000 | 0.004 | Â | Â | G2Â M checkpoint |
x | x | 2.15 | 2.27 | <0.001 | <0.001 | 0.000 | 0.000 | x | Â | Allograft rejection |
x | x | 2.12 | 2.33 | <0.001 | <0.001 | 0.000 | 0.000 | x | Â | Inflammatory response |
x | x | 2.08 | 1.99 | <0.001 | <0.001 | 0.000 | 0.001 | x | Â | IL6 JAK STAT3 signaling |
x | x | 1.99 | 1.90 | <0.001 | <0.001 | 0.000 | 0.001 | Â | Â | Epithelial mesenchymal transition |
x | x | 1.97 | 1.97 | <0.001 | <0.001 | 0.000 | Â | x | Â | TNFA signaling via NFKB |
x | x | 1.88 | 1.75 | <0.001 | <0.001 | 0.000 | Â | Â | Â | Mitotic spindle |
x | x | 1.86 | 2.10 | <0.001 | <0.001 | 0.000 | 0.000 | Â | Â | Complement |
x | x | 1.86 | 2.10 | <0.001 | <0.001 | 0.000 | Â | x | Â | Kras signaling up |
x | x | 1.81 | 1.41 | 0.002 | 0.045 | 0.001 | Â | Â | Â | Protein secretion |
x | x | 1.72 | 1.89 | <0.001 | <0.001 | 0.004 | 0.001 | Â | Â | Apoptosis |
x | x | 1.63 | –1.34 | 0.001 | 0.026 | 0.008 | 0.091 |  | x | MTORC1 signaling |
x | x | 1.60 | 2.35 | 0.001 | <0.001 | 0.011 | 0.000 | x | Â | Interferon gamma response |
x | x | 1.58 | 1.61 | 0.021 | 0.021 | 0.013 | 0.011 | Â | x | Angiogenesis |
x | x | 1.50 | 1.48 | 0.006 | 0.012 | 0.027 | 0.035 | Â | Â | Coagulation |
x | Â | 1.48 | Â | 0.012 | Â | 0.030 | Â | Â | Â | Unfolded protein response |
x | Â | 1.43 | Â | 0.015 | Â | 0.047 | Â | Â | Â | MYC targets V1 |
x | Â | 1.41 | Â | 0.024 | Â | 0.051 | Â | Â | x | Androgen response |
x | Â | 1.36 | Â | 0.027 | Â | 0.073 | Â | x | Â | IL2 STAT5 signaling |
x | x | 1.34 | 1.68 | 0.024 | <0.001 | 0.084 | Â | Â | Â | P53 pathway |
x | x | −1.45 | −1.72 | 0.016 | <0.001 | 0.036 | 0.004 |  | x | Peroxisome |
x |  | −1.56 |  | <0.001 |  | 0.000 |  |  |  | Myogenesis |
x | x | −1.65 | −2.14 | <0.001 | <0.001 | 0.000 | 0.000 |  | x | Bile acid metabolism |
x | x | −1.86 | –1.46 | <0.001 | 0.003 | 0.000 | 0.038 |  |  | Xenobiotic metabolism |
x | x | –2.17 | –2.40 | <0.001 | <0.001 | 0.000 | 0.000 |  | x | Fatty acid metabolism |
x | x | –2.44 | −2.15 | <0.001 | <0.001 | 0.000 | 0.000 |  | x | Oxidative phosphorylation |
x | x | −3.06 | −2.38 | <0.001 | <0.001 | 0.000 | 0.000 |  | x | Adipogenesis |
 | x |  | 2.08 |  | <0.001 |  | 0.000 | x |  | Interferon alpha response |
 | x |  | 1.72 |  | <0.001 |  | 0.005 |  |  | Heme metabolism |
 | x |  | 1.63 |  | 0.001 |  | 0.010 |  |  | Apical junction |
 | x |  | 1.50 |  | 0.007 |  | 0.031 |  | x | Hypoxia |
 | x |  | –1.77 | <0.001 |  |  | 0.002 |  |  | Spermatogenesis |