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Table 4 Concentrations of CRP according to the HNF1A carrier status among participants with diabetes

From: Assessing the association of the HNF1A G319S variant with C-reactive protein in Aboriginal Canadians: a population-based epidemiological study

 

Beta

SE

CRP [95% CI] (mg/L)*

p

   

G/G319

S/G + S/S319

 

Model 1†

-0.2162

0.1847

4.79 (3.33-6.88)

3.86 (2.69-5.54)

0.24

Model 2‡

-0.3514

0.2354

5.05 (3.18-8.01)

3.52 (2.22-5.58)

0.13

Model 3§

-0.2971

0.2286

4.96 (3.17-7.77)

3.69 (2.36-5.77)

0.20

Model 4∥

-0.0109

0.1786

4.44 (3.13-6.30)

4.39 (3.09-6.23)

0.95

  1. *Least square mean CRP values are back-transformed after using log-transformed CRP to calculate p-values. Group sample sizes of 77 (G/G319) and 47 (S/G + S/S319) have 99.9% power to detect a difference between mean CRP concentrations ± standard deviations of 4.79 ± 1.03 (G/G319) and 3.86 ± 0.93 (S/G + S/S319) at a significance level of 0.05. †Model 1: unadjusted ‡Model 2: adjusted for age, sex, log 2-h post-load glucose §Model 3: adjusted for model 2 variable and waist circumference ∥Model 4: adjusted for model 3 variables and log serum amyloid A