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Figure 6 | Cardiovascular Diabetology

Figure 6

From: The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive rats

Figure 6

Renal histopathology in DSS rats after 4 weeks of treatment demonstrated beneficial effects of AC3174. (A) Low salt diet exhibiting normal-to-mild scattered sclerosis. (B) High salt diet showing diffuse severe sclerosis. (C) AC3174 treatment on a background of a high salt diet displaying scattered moderate sclerosis. (D) Captopril treatment on a background of a high salt diet showing diffuse mild sclerosis. (E) AC3174 plus captopril treatment on a background of a high salt diet showing scattered mild sclerosis. (F) GLP-1 treatment on a background of a high salt diet exhibiting scattered mild sclerosis. N = 5 to 12 rats per group.

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Cardiovascular Diabetology

ISSN: 1475-2840