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Table 3 Changes in baseline characteristics seen after treatment with metoprolol.

From: Metoprolol compared to carvedilol deteriorates insulin-stimulated endothelial function in patients with type 2 diabetes - a randomized study

 

Before metoprolol

(N = 10)

After metoprolol

(N = 10)

% Change after treatment

P-value

Body weight (kg)

97.9 ± 5.76

99.7 ± 5.88

1.8%

0.02

BMI (Kg/m²)

32.22 ± 1.84

32.84 ± 1.95

1.9%

0.03

Systolic BP (mm Hg)

143.4 ± 5.12

142.8 ± 5.56

-0.4%

0.90

Diastolic BP (mm Hg)

70.5 ± 4.67

64 ± 3.84

-9.2%

0.04

Heart rate (beats/min)

69.4 ± 3.31

65.5 ± 6.74

-5.6%

0.01

Fasting glucose (mmol/L)

8.53 ± 0.99

8.67 ± 1.14

1.6%

0.90

Fasting insulin (μU/L)

10.82 ± 2.14

14.83 ± 4.75

37.1%

0.60

Hb A1c (%)

7.29 ± 0.42

7.51 ± 0.62

3.0%

0.77

Total Cholesterol (mmol/L)

3.93 ± 0.25

3.81 ± 0.27

-3.1%

0.59

LDL (mmol/L)

2.25 ± 0.27

1.99 ± 0.32

-11.6%

0.17

HDL (mmol/L)

1.09 ± 0.10

1.06 ± 0.12

-2.8%

0.10

TG (mmol/L)

1.33 ± 0.26

1.71 ± 0.35

28.6%

0.04

CRP (mmol/L)

6.80 ± 2.38

4.56 ± 1.56

-32.9%

0.19

  1. T2DM: Patients with Type 2 Diabetes; M/F: Male/Female; ACE inhibitors: Angiotensin Converting Enzyme inhibitors; AT2B: Angiotensin 2 Blockers; BMI: Body Mass Index, BP: Blood Pressure; Hb A1c: Glycosylated Hemoglobin A1c; LDL: Low Density Lipoprotein; HDL: High Density Lipoprotein; TG: TriGlyceride; CRP: C-Reactive Protein.