Figure 2

Regression-correlation network of continuous and binary data. A pruned visualization of the correlation network from regression modeling. Unlike in Figure 1, the data were not adjusted for gender prior to the analysis. Each variable was converted to a surrogate linear predictor before computations. The symbols in the figure correspond to the source of information: directly observed variables are filled, whereas derived variables are denoted by open symbols. A circle is used for continuous quantities, and a diamond for binary traits. The width and color of the links indicate the association magnitude and type, as shown in the legend. The r denotes the correlation of the linear predictors and is not comparable with Figure 1. Abbreviations: history of macrovascular disease (MVD), systolic (SBP) and diastolic (DBP) blood pressure, anti-hypertensive treatment (AHT) and soluble receptor for advanced glycation end-products (SRAGE). Visualized with the Himmeli software [47].