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Table 2 Cox's proportional hazards regression model for mortality in the PMI cohort.

From: The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction

 

Coefficient

SE

Wald

df

Significance

Hazard Ratio

95% CI for Hazard Ratio

Age

0.018

0.016

1.40

1

0.237

1.02

0.99–1.05

Gender

0.587

0.270

4.71

1

0.030

1.80

1.06–3.06

ACE inhibitor (No/Yes)

0.235

0.229

1.06

1

0.303

1.27

0.81–1.98

LVEF (1–4 days post-MI)

-0.013

0.011

1.48

1

0.224

0.99

0.97–1.01

Log10 NTproBNP*

1.55

0.409

14.3

1

<0.001

4.70

2.11–10.5

Log10 peak creatine kinase*

1.11

0.338

10.8

1

0.001

3.04

1.56–5.88

Creatinine clearance

-0.900

0.384

5.49

1

0.019

0.406

0.19–0.86

Ethnicity (European v non-European)

1.05

0.597

3.11

1

0.078

2.86

0.89–9.21

Type 2 Diabetes

0.847

0.602

1.98

1

0.159

2.33

0.72–7.59

UCP2 G-866A genotype

  

4.91

2

0.086

  

   GG v AA

1.64

0.747

4.79

1

0.029

5.13

1.19–22.2

   GG v GA

1.16

0.684

2.89

1

0.089

3.19

0.841–12.2

Diabetes × UCP2 genotype

  

6.92

2

0.031

  

   Diabetes × UCP2 genotype(GG v AA)

1.52

0.725

4.40

1

0.036

4.59

1.10–18.9

   Diabetes × UCP2 genotype(GG v GA)

2.09

0.826

6.40

1

0.011

8.06

1.60–40.0

  1. * Hazard Ratio represents the change in risk for every 10-fold increase in measurement level.
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Cardiovascular Diabetology

ISSN: 1475-2840