Does the association of the triglyceride to high-density lipoprotein cholesterol ratio with fasting serum insulin differ by race/ethnicity?

Table 2 Metric and standardized regression coefficients of triglycerides, HDL-C, and the TG/HDL-C ratio on FSI by sex and race/ethnicity

	Non-Hispanic White (NHW)			Non-Hispanic Black (NHB)			Mexican American (MA)			P-value‡
	β_m*	SE	β_s†	β_m	SE	β_s	β_m	SE	β_s	NHB vs. NHW	MA vs. NHW	MA vs. NHB	Interaction§
Men	n = 770			n = 243			n = 346
Triglycerides (mmol/L)	0.22	0.03	0.25	0.30	0.06	0.23	0.28	0.06	0.31	0.13	0.63	0.29	0.22
HDL-C (mmol/L)	-0.51	0.07	-0.24	-0.45	0.12	-0.20	-0.46	0.10	-0.21	0.98	0.88	0.94	0.98
TG/HDL-C ratio	0.19	0.02	0.27	0.24	0.04	0.25	0.22	0.04	0.31	0.14	0.75	0.32	0.27
Women	n = 737			n = 236			n = 320
Triglycerides (mmol/L)	0.26	0.07	0.26	0.28	0.08	0.24	0.44	0.05	0.42	0.67	0.03	0.05	0.23
HDL-C (mmol/L)	-0.46	0.07	-0.25	-0.32	0.11	-0.18	-0.61	0.12	-0.28	0.72	0.31	0.26	0.60
TG/HDL-C ratio	0.24	0.05	0.30	0.21	0.05	0.24	0.34	0.03	0.40	0.55	0.05	0.05	0.26

HDL = high-density lipoprotein; FSI = fasting serum insulin. W = non-Hispanic white, B = non-Hispanic black, M = Mexican American.
* β_m – metric regression coefficient. SE = standard error.
† β_s – standardized regression coefficient. β_m and β_s were adjusted for age, education attainment, poverty-income ratio, smoking, systolic blood pressure, C-reactive protein, and waist circumference. All individual regression coefficients were significant at α = 0.05 level.
‡ Significance level with Bonferroni adjustment for multiple comparisons is 0.05/3 ≈ 0.017.
§Interaction between race/ethnicity and TG/HDL-C ratio.

ISSN: 1475-2840