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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Diabetes alters vascular mechanotransduction: pressure-induced regulation of mitogen activated protein kinases in the rat inferior vena cava

Figure 4

Diabetes alters loading-induced Jnk phosphorylation in the IVC. The basal (control) and pressure-induced phosphorylation of the JNK-MAPK in venae cavae from non-diabetic lean Zucker (LNZ) and diabetic obese syndrome X Zucker (OSXZ) rats. Phosphorylation status of A.) JNK2-MAPK, B.) JNK3-MAPK, and C.) JNK1-MAPK was calculated as phosphospecific optical density divided by the unpressurized non-diabetic control value. * Significantly different from unloaded venae cavae within the same group (P < 0.05). † Significantly different from corresponding non-diabetic venae cavae (P < 0.05). n = 6/group.

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Cardiovascular Diabetology

ISSN: 1475-2840