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Table 1 Effect of STZ-induced diabetes on percent body weight (BW) change, blood glucose levels (mg.dL-1), mean arterial pressure (mmHg), heart rate (beats per min), kidney weight/100 g BW, and plasma creatinine concentration (g.dL-1.kg-1 BW) at 14-days (Diab, 14-days) and 28-days (Diab, 28-days). (N = 6 in each group) * p ≤ 0.05 Vs control group.

From: Duration of streptozotocin-induced diabetes differentially affects p38-mitogen-activated protein kinase (MAPK) phosphorylation in renal and vascular dysfunction

Parameter

Control

Diab (14-days)

Diab (28-days)

BW change (%)

10 ± 3

-10 ± 3*

-13 ± 2*

Blood glucose (mg.dL-1)

84 ± 2

480 ± 3*

486 ± 11*

Mean arterial pressure (mmHg)

130 ± 3

120 ± 6

117 ± 2

HR (Beats per min)

419 ± 5

326 ± 7*

339 ± 10*

Kidney weight/100 g BW

0.72 ± 0.03

1.1 ± 0.05*

1.0 ± 0.03*

Plasma creatinine (mg.dL-1.kg-1)

2.4 ± 0.5

6.4 ± 3.5

4.5 ± 3.5