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Table 3 PAD and intermittent claudication according to MTHFR 677C>T genotype

From: Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes

 

677C/C n = 108

677C/T n = 30

OR (95% CI)

P*

PAD, left or right (n, %)

12 (11.1%)

8 (26.7%)

2.91 (1.06, 7.97)

0.042

   PAD, left (n, %)

7 (6.48%)

4 (13.3%)

2.22 (0.60, 8.16)

NS (0.25)

   PAD, right (n, %)

9 (8.33%)

7 (23.3%)

3.35 (1.13, 9.93)

0.047

Intermittent claudication (n, %)

6 (5.56%)

2 (6.67%)

1.20 (0.26, 5.64)

NS (0.68)

  1. * Fisher's exact test
  2. Abbreviations: OR, odds ratio; PAD, peripheral arterial disease; NS, not significant.
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Cardiovascular Diabetology

ISSN: 1475-2840