Table 2 Changes in glucose, insulin and haemodynamic parameters following an oral glucose load. Responses to glucose loading were quantified either as the maximum response during the 120 minutes observation period, as the area under the response profile (AUC) from 15 to 120 minute (comp. Figure 1, 2) or as insulinogenic index.
Max response | CC | CT/TT | P-value | 95% CI |
|---|---|---|---|---|
Blood glucose [mg dl-1] | 58.6 ± 6.6 | 57.0 ± 5.3 | 0.849 | -15.7/18.9 |
Serum insulin [μU dl-1] | 95.9 ± 16.9 | 118.3 ± 27.1 | 0.510 | -92.4/47.4 |
Heart rate [per min] | 8.7 ± 1.4 | 9.0 ± 0.7 | 0.834 | -3.4/2.7 |
Systolic blood pressure [mm Hg] | 6.5 ± 1.0 | 8.3 ± 0.8 | 0.173 | -4.5/0.9 |
Diastolic blood pressure [mm Hg] | -4.2 ± 1.3 | -3.8 ± 0.9 | 0.793 | -3.6/2.8 |
Stroke volume [ml] | 15.2 ± 0.8 | 21.0 ± 3.0 | 0.090 | -12.7/1.0 |
Cardiac output [l min-1] | 1.2 ± 0.2 | 2.0 ± 0.2 | 0.071 | -1.3/-0.2 |
Total peripheral resistance [dyne sec cm-5] | -300 ± 64.4 | -289 ± 33.8 | 0.880 | -159/137 |
Total electromechanical systole [ms] | -16.3 ± 2.2 | -17.1 ± 1.8 | 0.772 | -5.0/6.7 |
AUC response | CC | CT/TT | P-value | 95% CI |
Blood glucose [mg dl-1] | 3184 ± 740 | 3136 ± 452 | 0.954 | -1694/1792 |
Serum insulin [μU dl-1] | 7388 ± 1425 | 7223 ± 1219 | 0.930 | -3722/4052 |
Heart rate [per min] | 425 ± 122 | 582 ± 71 | 0.259 | -439/125 |
Systolic blood pressure [mm Hg] | 521 ± 90 | 752 ± 73 | 0.058 | -472/8 |
Diastolic blood pressure [mm Hg] | 367 ± 116 | 302 ± 87 | 0.346 | -435/159 |
Stroke volume [ml] | 836 ± 195 | 764 ± 202 | 0.800 | -517/662 |
Cardiac output [l min-1] | 88 ± 19 | 104 ± 12 | 0.478 | -63/31 |
Total peripheral resistance [dyne sec cm-5] | 1383 ± 122.4 | 1216 ± 77.3 | 0.273 | -21877/6536 |
Total electromechanical systole [ms] | -1242 ± 259 | -1499 ± 172 | 0.408 | -376/888 |
CC | CT/TT | P-value | 95% CI | |
Insulinogenic index | 2.43 ± 0.87 | 1.96 ± 0.49 | 0.628 | -2.468/1.525 |