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Figure 2 | Cardiovascular Diabetology

Figure 2

From: Exenatide induces aortic vasodilation increasing hydrogen sulphide, carbon monoxide and nitric oxide production

Figure 2

Role of GLP-1 receptor and endothelial denudation in the vasodilatation due to exenatide. Exenatide concentration-relaxation curves of vessels treated with exenatide only (▲) and vessels preicubated with GLP-1R anatagonist exendin(9–39) (■) (A). Vasodilation evoked by exenatide in endothelium-intact and endothelium-denuded vessels (B). 23.9, 71.7, 310, 788, 1980, 3170 nanomoles of exenatide were used to relax the vessels (n = 5 of each experiment), *P < 0.01 compared to exenatide only (at respective concentration of exenatide).

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Cardiovascular Diabetology

ISSN: 1475-2840