Table 1 General features of SHAM and STZ rats

Body mass (g)

538 ± 15

375 ± 13*

Tibial length (mm)

45.4 ± 0.6

42.2 ± 0.6*

Lung mass (g)

2.05 ± 0.09

1.89 ± 0.06

Lung mass/body mass (%)

0.38 ± 0.02

0.52 ± 0.03*

Heart mass (g)

1.49 ± 0.05

1.16 ± 0.04*

Heart mass/body mass (%)

0.28 ± 0.01

0.31 ± 0.01*

RV wall thickness (mm)

1.33 ± 0.04

1.16 ± 0.06*

LV wall thickness (mm)

3.80 ± 0.09

3.74 ± 0.09

Septal wall thickness (mm)

3.18 ± 0.07

3.14 ± 0.11

RV thickness/heart mass (mm g^-1)

0.91 ± 0.03

1.02 ± 0.06

LV thickness/heart mass (mm g^-1)

2.60 ± 0.10

3.26 ± 0.12*

Septal thickness/heart mass (mm g^-1)

2.16 ± 0.07

2.74 ± 0.13*

Blood glucose (mM)

6.8 ± 0.1

29.6 ± 0.5*

Systolic blood pressure (mmHg)

129 ± 2.8

125 ± 2.9

Diastolic blood pressure (mmHg)

84 ± 2.2

82 ± 2.2

Mean arterial blood pressure (mmHg)

103 ± 2.3

102 ± 2.6

Heart rate in vivo (beats min^-1)

346 ± 16

302 ± 5*

Heart rate in vitro (beats min^-1)

175 ± 7

156 ± 5*