Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease

Table 4 Association of medications for diabetes, coronary artery disease and plasma levels of cyclophilin

Medication*	Mean	Median	Std Dev	Min range	Max range	T value	P value
(i) Antiplatelets
Yes	15.31	15.58	3.2	9.03	5.54	1.52	0.12
No	14.67	15.12	3.6	5.54	19.93
(ii) Statins
Yes	15.25	15.58	3.3	9.03	22.73	1.28	0.20
No	14.71	15.38	3.5	5.54	19.93
(iii) Antihypertensive
Yes	15.14	15.54	3.3	6.92	22.73	0.84	0.40
No	14.78	15.4	3.5	5.54	19.93
(iv) Metformin
Yes	15.75	16.58	3.2	10.28	22.73	4.00	<0.001
No	14.1	14.33	3.5	5.54	19.92

*Medications were grouped into (i) antiplatelet aggregating agents (Ecospirin, Clopidogrel, Cilostazol) (ii) Statins (atorvastatin, lovastatin) (iii) Antihypertensive agents (Calcium channel blockers, ACE inhibitors, vasodilators and (iv) metformin derivatives (Glucophage, glycimet).

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