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Table 3 Patient demographics and clinical characteristics in the pool of saxagliptin add-on to metformin studies

From: Assessment of the cardiovascular safety of saxagliptin in patients with type 2 diabetes mellitus: pooled analysis of 20 clinical trials

Characteristic, n (%)

All SAXA

Control

(n = 2981)

(n = 2190)

Age, y

  

  <65

2397 (80.4)

1733 (79.1)

  ≥65

584 (19.6)

457 (20.9)

  ≥75

86 (2.9)

62 (2.8)

Women

1533 (51.4)

1070 (48.9)

Race

  

  White

2031 (68.1)

1426 (65.1)

  Asian

549 (18.4)

469 (21.4)

  Black

109 (3.7)

58 (2.6)

  Other

292 (9.8)

237 (10.8)

BMI, kg/m2

  

  <30

1438 (48.2)

1114 (50.9)

  ≥30

1541 (51.7)

1074 (49.0)

  Not reported

2 (<0.1)

2 (<0.1)

Duration of T2DM, y

  

  ≤1.5

828 (27.8)

504 (23.0)

  ≤3

1198 (40.2)

833 (38.0)

  >3– < 5

475 (15.9)

386 (17.6)

  ≥5

1308 (43.9)

971 (44.3)

  ≥10

489 (16.4)

391 (17.9)

Creatinine clearance, mL/min

  

  30– < 50

28 (0.9)

14 (0.6)

  50–80

493 (16.5)

405 (18.5)

  >80

2457 (82.4)

1768 (80.7)

  Not reported

3 (0.1)

3 (0.1)

  1. BMI = body mass index; SAXA = saxagliptin; T2DM = type 2 diabetes mellitus.