Skip to main content
Figure 5 | Cardiovascular Diabetology

Figure 5

From: The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms

Figure 5

Effects of sitagliptin on AMPK- and AMPK-mediated Akt activation and MAPK phosphorylation in the aorta. Phosphorylative and total protein expression of AMPK (A), Akt (C), p38 (E) and ERK1/2 (G) in the aortic tissue of ApoE-/- mice. Quantitative analysis of pAMPK/AMPK (B), pAkt/Akt (D), pp38/p38 (F) and pERK1/2/ERK1/2 (H) in aortic tissue (n = 4 each). Values are mean ± SD; *p < 0.05, **p < 0.01.

Back to article page

Cardiovascular Diabetology

ISSN: 1475-2840