Table 2 Echocardiography parameters in CON and STZ-DM rats

HR (bpm)

330.7 ± 13.6

314.4 ± 26.4

349.7 ± 8.5

297.9 ± 8^a

328.3 ± 18.7

277.7 ± 9.3^a

LVDD/BW (mm/kg)

21.90 ± 0.4

30.90 ± 1.1^b

19.70 ± 0.4

32.20 ± 1.5^b

19.91 ± 0.63

35.25 ± 1.9^b

LVSD/BW (mm/kg)

12.40 ± 0.5

19.50 ± 1.3^b

11.20 ± 0.3

21.20 ± 1.3^b

12.21 ± 0.39

25.64 ± 1.5^b

IVSD/BW (mm/kg)

2.68 ± 0.13

3.08 ± 0.21

2.63 ± 0.14

2.99 ± 0.15

2.24 ± 0.11

2.50 ± 0.21

IVSS/BW (mm/kg)

5.35 ± 0.32

5.98 ± 0.47^a

5.19 ± 0.28

5.55 ± 0.34

4.24 ± 0.25

4.47 ± 0.32

LVmass/BW (g/kg)

1.21 ± 0.03

0.80 ± 0.06^b

1.20 ± 0.07

1.45 ± 0.08^a

1.12 ± 0.06

1.25 ± 0.1

RWT/BW (mm/kg)

0.44 ± 0.02

0.37 ± 0.01^a

0.43 ± 0.02

0.33 ± 0.01^b

0.39 ± 0.02

0.27 ± 0.01^b

FS (%)

43.7 ± 2.2

37.1 ± 2.4^a

43.2 ± 1.4

32.6 ± 1.3^a

38.8 ± 1.1

27.4 ± 0.7^a

E/A ratio

1.98 ± 0.07

1.50 ± 0.05^a

1.98 ± 0.13

1.55 ± 0.12^a

1.83 ± 0.15

1.35 ± 0.02^a

IVRT (msec)

26.3 ± 2

34.4 ± 3^a

25.3 ± 1.7

32.9 ± 2.8^a

27.7 ± 1.8

38.1 ± 2.9^a

DecT (msec)

45.7 ± 0.8

41.6 ± 2.6

41.2 ± 2.9

47.9 ± 3.2

44.2 ± 2.8

43.3 ± 2.5