Table 2 Data from the female diabetic population and age-matched controls: menopause influence
From: Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women
Female control group | Female diabetic group | Diabetic vs control (P) | ||||||
|---|---|---|---|---|---|---|---|---|
Parameters | Pre-M (n = 16) | Post-M (n = 19) | P | Pre-M (n = 8) | Post-M (n = 45) | P | Pre-menopausal | Post- menopausal |
Age (years) | 45.63 ± 1.12 | 62.37 ± 1.35 | 0.000 | 43.88 ± 1.29 | 63.44 ± 1.20 | 0.000 | 0.349 | 0.345 |
BMI (Kg/m2) | 26.93 ± 1.21 | 27.21 ± 0.85 | 0.472 | 29.43 ± 2.44 | 30.24 ± 0.67 | 0.578 | 0.221 | 0.013 |
WC (cm) | 91.38 ± 2.86 | 93.06 ± 2.75 | 0.575 | 100.57 ± 4.93 | 104.66 ± 2.27 | 0.081 | 0.103 | 0.000 |
SBP (mmHg) | 132.69 ± 5.62 | 153.56 ± 4.61 | 0.004 | 120.38 ± 7.22 | 140.58 ± 3.91 | 0.048 | 0.187 | 0.113 |
DBP (mmHg) | 84.25 ± 3.20 | 90.89 ± 2.52 | 0.175 | 72.25 ± 3.14 | 72.82 ± 2.02 | 0.519 | 0.027 | 0.000 |
Glycemia (mmol/L) | 4.92 ± 0.10 | 5.31 ± 0.14 | 0.038 | 10.80 ± 1.65 | 10.67 ± 0.64 | 0.832 | 0.000 | 0.000 |
HbA1c (%) | — | — | — | 9.03 ± 1.08 | 9.23 ± 0.30 | 0.477 | — | — |
Total-c (mmol/L) | 5.08 ± 0.16 | 5.48 ± 0.21 | 0.364 | 4.68 ± 0.44 | 4.93 ± 0.16 | 0.725 | 0.313 | 0.090 |
TGs (mmol/L) | 1.02 ± 0.08 | 1.13 ± 0.10 | 0.455 | 1.51 ± 0.31 | 2.08 ± 0.17 | 0.467 | 0.066 | 0.003 |
LDL-c (mmol/L) | 3.21 ± 0.17 | 3.47 ± 0.19 | 0.514 | 2.71 ± 0.35 | 2.69 ± 0.15 | 0.997 | 0.164 | 0.007 |
Ox-LDL (U/L) | 29.13 ± 1.76 | 36.46 ± 2.98 | 0.044 | 34.83 ± .58 | 31.89 ± 1.61 | 0.993 | 0.897 | 0.339 |
Non-HDL-c (mmol/L) | 3.68 ± 0.17 | 4.01 ± 0.20 | 0.390 | 3.36 ± 0.45 | 3.60 ± 0.17 | 0.781 | 0.236 | 0.243 |
PON1 activity | 415.66 ± 26.78 | 477.17± 32.14 | 0.420 | 443.94 ± 31.40 | 498.39 ± 35.22 | 0.089 | 0.527 | 0.916 |