From: Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women
Control group | Diabetic group | Diabetic vs control (P) | ||||||
---|---|---|---|---|---|---|---|---|
Parameters | Male (n = 39) | Female (n = 35) | P | Male (n = 57) | Female (n = 53) | P | Male | Female |
Age (years) | 59.97 ± 1.02 | 54.71 ± 1.68 | 0.100 | 58.88 ± 1.34 | 60.49 ± 1.42 | 0.524 | 0.453 | 0.013 |
Gender (%M/%F) | 52.70 | 47.30 | — | 51.82 | 48.18 | — | — | — |
BMI (Kg/m2) | 27.89 ± 0.72 | 27.09 ± 0.71 | 0.704 | 30.37 ± 0.65 | 30.12 ± 0.67 | 0.788 | 0.013 | 0.002 |
WC (cm) | 101.32 ± 1.75 | 92.26 ± 1.96 | 0.003 | 110.36 ± 1.70 | 104.02 ± 2.05 | 0.020 | 0.000 | 0.000 |
SBP (mmHg) | 145.28 ± 3.08 | 143.74 ± 3.98 | 0.010 | 136.86 ± 2.95 | 137.53 ± 3.61 | 0.942 | 0.002 | 0.000 |
DBP (mmHg) | 87.10 ± 1.54 | 87.76 ± 2.06 | 0.654 | 73.54 ± 1.69 | 72.74 ± 1.77 | 0.745 | 0.000 | 0.000 |
Glycemia (mmol/L) | 5.58 ± 0.08 | 5.12 ± 0.09 | 0.000 | 9.70 ± 0.48 | 10.69 ± 0.59 | 0.191 | 0.000 | 0.000 |
HbA1c (%) | — | — | — | 8.13 ± 0.25 | 9.20 ± 0.30 | 0.007 | — | — |
Total-c (mmol/L) | 5.71 ± 0.15 | 5.30 ± 0.14 | 0.121 | 4.75 ± 0.15 | 4.89 ± 0.15 | 0.526 | 0.000 | 0.129 |
TGs (mmol/L) | 1.28 ± 0.08 | 1.08 ± 0.06 | 0.118 | 1.85 ± 0.15 | 1.99 ± 0.15 | 0.406 | 0.002 | 0.000 |
LDL-c (mmol/L) | 3.70 ± 0.15 | 3.36 ± 0.13 | 0.222 | 2.69 ± 0.14 | 2.69 ± 0.14 | 0.996 | 0.000 | 0.012 |
Ox-LDL (U/L) | 52.65 ± 2.60 | 33.23 ± 1.92 | 0.000 | 32.58 ± 1.78 | 32.42 ± 1.84 | 1.000 | 0.000 | 0.401 |
Non-HDL-c (mmol/L) | 4.28 ± 0.15 | 3.86 ± 0.14 | 0.110 | 3.50 ± 0.16 | 3.56 ± 0.16 | 0.635 | 0.004 | 0.257 |
PON1 activity | 519.66 ± 18.63 | 449.05 ± 21.66 | 0.034 | 426.01 ± 20.27 | 490.17 ± 30.31 | 0.077 | 0.004 | 0.780 |