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Table 1 Data from the diabetic population and age and gender-matched controls

From: Diabetes abrogates sex differences and aggravates cardiometabolic risk in postmenopausal women

  

Control group

  

Diabetic group

 

Diabetic vs control (P)

Parameters

Male (n = 39)

Female (n = 35)

P

Male (n = 57)

Female (n = 53)

P

Male

Female

Age (years)

59.97 ± 1.02

54.71 ± 1.68

0.100

58.88 ± 1.34

60.49 ± 1.42

0.524

0.453

0.013

Gender (%M/%F)

52.70

47.30

51.82

48.18

BMI (Kg/m2)

27.89 ± 0.72

27.09 ± 0.71

0.704

30.37 ± 0.65

30.12 ± 0.67

0.788

0.013

0.002

WC (cm)

101.32 ± 1.75

92.26 ± 1.96

0.003

110.36 ± 1.70

104.02 ± 2.05

0.020

0.000

0.000

SBP (mmHg)

145.28 ± 3.08

143.74 ± 3.98

0.010

136.86 ± 2.95

137.53 ± 3.61

0.942

0.002

0.000

DBP (mmHg)

87.10 ± 1.54

87.76 ± 2.06

0.654

73.54 ± 1.69

72.74 ± 1.77

0.745

0.000

0.000

Glycemia (mmol/L)

5.58 ± 0.08

5.12 ± 0.09

0.000

9.70 ± 0.48

10.69 ± 0.59

0.191

0.000

0.000

HbA1c (%)

8.13 ± 0.25

9.20 ± 0.30

0.007

Total-c (mmol/L)

5.71 ± 0.15

5.30 ± 0.14

0.121

4.75 ± 0.15

4.89 ± 0.15

0.526

0.000

0.129

TGs (mmol/L)

1.28 ± 0.08

1.08 ± 0.06

0.118

1.85 ± 0.15

1.99 ± 0.15

0.406

0.002

0.000

LDL-c (mmol/L)

3.70 ± 0.15

3.36 ± 0.13

0.222

2.69 ± 0.14

2.69 ± 0.14

0.996

0.000

0.012

Ox-LDL (U/L)

52.65 ± 2.60

33.23 ± 1.92

0.000

32.58 ± 1.78

32.42 ± 1.84

1.000

0.000

0.401

Non-HDL-c (mmol/L)

4.28 ± 0.15

3.86 ± 0.14

0.110

3.50 ± 0.16

3.56 ± 0.16

0.635

0.004

0.257

PON1 activity

519.66 ± 18.63

449.05 ± 21.66

0.034

426.01 ± 20.27

490.17 ± 30.31

0.077

0.004

0.780

  1. Results are presented as media ± SEM. Independent samples T-test and Mann–Whitney test for normalized and non-normalized samples, respectively. P adjusted for age and BMI (ANCOVA) when adequate (when p<0.05): for age when comparing female diabetic vs female control subjects; for BMI when comparing diabetic vs control (both for male and for female). BMI, body mass index; HbA1c, glycated hemoglobin; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-c, low-density lipoprotein cholesterol; Ox-LDL, oxidized low-density lipoprotein; TGs, triglycerides; Total-c, total cholesterol; WC, waist circumference.