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Table 2 General characteristics of male and female T2DM subjects according to follow-up

From: Vitamin D supplementation as an adjuvant therapy for patients with T2DM: an 18-month prospective interventional study

 

MALES

FEMALES

Baseline

6 Months

12 Months

18 Months

P val

Baseline

6 Months

12 Months

18 Months

P val

N

34

    

58

    

DMT2 Duration (years)

7.3 ± 6.5

    

7.1 ± 5.5

    

Age (years)

56.6 ± 8.7

    

51.2 ± 10.6

    

Systolic BP (mmHg)

127.0 ± 15.2

125.2 ± 17.5

131.7 ± 16.2

124.9 ± 8.5

0.05

127.3 ± 13.4

125.4 ± 17.2

126.3 ± 12.9

126.7 ± 7.8

0.90

Diastolic BP (mmHg)

79.3 ± 7.4

80.4 ± 10.1

80.7 ± 8.5

76.2 ± 5.1

0.10

79.7 ± 7.3

78.0 ± 10.1

78.9 ± 10.1

77.9 ± 7.1

0.72

BMI (kg/m2)

29.0 ± 3.3

29.2 ± 3.7

29.1 ± 3.7

29.7 ± 4.3

0.41

34.2 ± 4.9

34.4 ± 4.6

34.7 ± 4.5

3.4.9 ± 4.7

0.30

Glucose (mmol/l)

10.9 ± 4.6

10.8 ± 3.8

12.8 ± 3.9

11.3 ± 5.2

0.11

10.6 ± 3.4

11.2 ± 4.6

11.2 ± 4.1

10.8 ± 3.9

0.70

T Cholesterol (mmol/l)

5.4 ± 1.2

5.5 ± 1.6

5.0 ± 1.0

4.9 ± 1.1

0.11

5.5 ± 0.84

5.3 ± 1.0

4.9 ± 0.99*

4.9 ± 1.2*

<0.001

Triglycerides (mmol/l)

1.8 ± 0.31

2.1 ± 0.32

2.0 ± 0.29

1.8 ± 0.32

0.25

1.9 ± 0.35

2.0 ± 0.33

1.7 ± 0.25

1.9 ± 0.34

0.14

HDL-Chol (mmol/l)

1.4 ± 0.29

1.1 ± 0.07

1.1 ± 0.11

1.1 ± 0.12

0.10

1.0 ± 0.12

1.1 ± 0.13

1.1 ± 0.13

1.2 ± 0.17

0.16

LDL-Chol (mmol/l)

4.2 ± 1.5

4.1 ± 1.4

4.0 ± 1.9

4.1 ± 2.4

0.68

4.4 ± 0.80

4.0 ± 0.77

3.6 ± 0.90*

3.6 ± 0.77*

0.004

Corr. Calcium (mmol/l)

2.2 ± 0.22

2.4 ± 0.19

2.5 ± 0.27*

2.5 ± 0.10*

0.03

2.4 ± 0.21

2.4 ± 0.16

2.5 ± 0.19

2.5 ± 0.17

0.06

Albumin (g/L)

47.0 ± 7.9

43.9 ± 9.0

42.3 ± 3.0

42.6 ± 4.4

0.11

41.6 ± 4.5

38.3 ± 3.4*

39.4 ± 3.9*

37.7 ± 4.0*

<0.001

Insulin (IU/ml)

15.2 ± 1.9

18.9 ± 2.2

24.5 ± 2.1

21.5 ± 2.1

0.23

13.0 ± 2.1

19.0 ± 2.4

28.5 ± 1.6*

22.0 ± 2.2*

0.001

PTH (pmole/l)

1.1 ± 0.32

0.88 ± 0.20

0.89 ± 0.23

0.91 ± 0.24

0.06

1.4 ± 0.44

0.99 ± 0.34

0.97 ± 0.35

0.98 ± 0.32

0.09

HOMA-IR

6.8 ± 0.86

8.2 ± 0.96

11.1 ± 0.99

12.2 ± 1.1

0.32

5.8 ± 1.0

8.2 ± 0.99

12.4 ± 0.97*

11.2 ± 1.3*

0.01

HOMA β function (%)

52.0 ± 12.9

69.5 ± 10.7

66.1 ± 8.7

85.9 ± 15.3

0.12

50.6 ± 7.8

74.4 ± 18.1

91.6 ± 9.8*

86.3 ± 15.2*

0.004

25-(OH) D (nmol/l)

30.9 ± 1.4

55.7 ± 1.3*

50.6 ± 1.3*

55.7 ± 1.2*

<0.001

33.7 ± 1.6

59.7 ± 1.4*

46.7 ± 1.5*

54.9 ± 1.5*

<0.001

Magnesium (mmol/l)

0.71 ± 0.19

0.7 ± 0.07

0.70 ± 0.04

0.71 ± 0.05

0.90

0.69 ± 0.08

0.65 ± 0.08

0.65 ± 0.04

0.70 ± 0.19

0.73

Phosphorus (mmol/l)

1.20 ± 0.25

1.15 ± 0.21

1.05 ± 0.22

1.04 ± 0.19*

0.009

1.15 ± 0.22

1.20 ± 0.21

1.17 ± 0.22

1.16 ± 0.25

0.52

  1. Note: Data presented as mean ± SD; * denotes significance compared to baseline; # denotes significance compared to 6 months; P-value significant at <0.05.
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Cardiovascular Diabetology

ISSN: 1475-2840