| 0 | 1 | 2 | 3 | 4/5 | P# |
---|---|---|---|---|---|---|
No. of patients | 77 | 158 | 155 | 133 | 72 | Â |
Male gender, n (%) | 28 (36.4%) | 64 (40.5%) | 69 (44.5%) | 68 (51.1%)* | 45 (62.5%)*** | <0.001 |
Age (years) | 45.6±7.5 | 47.2±8.4 | 47.8±8.8 | 49.9±9.1** | 50.3±8.8** | <0.001 |
Smoking (packs/day*year) | 2.8±6.42 | 3.1±8.1 | 4.7±10.7 | 5.3±10.1* | 9.4±13.5*** | <0.001 |
Body Mass Index (kg/m2) | 21.9±1.9 | 23.7±2.4*** | 25.2±2.9*** | 26.6±2.9*** | 27.7±2.4*** | <0.001 |
Waist circumference (cm) | 74.7±6.1 | 78.5±7.8*** | 83.1±9.7*** | 88.6±9.2*** | 92.0±6.8*** | <0.001 |
Systolic BP (mmHg) | 103±10 | 121±26*** | 132±24*** | 137±23*** | 144±23*** | <0.001 |
Diastolic BP (mmHg) | 64±7 | 74±14*** | 78±14*** | 81±13*** | 84±12*** | <0.001 |
Fasting glucose (mmol/L) | 4.7±0.4 | 4.8±0.4 | 4.9±0.4* | 5.0±0.6*** | 5.4±0.6*** | <0.001 |
2hr pc glucose (mmol/L) | 6.5±1.8 | 6.9±1.5 | 7.0±1.9* | 7.5±1.7*** | 8.4±1.8*** | <0.001 |
Insulin (μU/mL) | 4.2±1.9 | 5.7±3.1*** | 7.3±4.6*** | 8.5±4.6*** | 11.5±5.7*** | <0.001 |
HOMA-IR | 0.9±0.4 | 1.3±0.7*** | 1.6±1.1*** | 1.9±1.1*** | 2.8±1.5*** | <0.001 |
Triglyceride (mmol/L) | 0.8±0.3 | 1.0±0.4*** | 1.3±0.6*** | 1.6±0.9*** | 2.4±1.1*** | <0.001 |
HDL cholesterol (mmol/L) | 1.5±0.3 | 1.2±0.3*** | 1.1±0.3*** | 1.0±0.2*** | 0.9±0.2*** | <0.001 |
Total cholesterol (mmol/L) | 4.6±0.9 | 4.8±1.1 | 4.8±0.9 | 4.8±1.1 | 4.9±0.9 | 0.177 |
LDL cholesterol (mmol/L) | 2.7±0.8 | 3.1±1.1 | 3.1±0.9 | 3.1±1.0 | 3.0±0.9 | 0.393 |