Table 3 Fasting hepatic glucose production, insulin-stimulated whole body glucose uptake, insulin-inhibited hepatic glucose production and plasma concentrations of metabolites and insulin in diabetic pigs fed saturated fat/cholesterol or unsaturated fat or starch enriched diets
| Â | Saturated fat plus cholesterol diet | Unsaturated fat diet | Starch diet |
|---|---|---|---|
Fasting plasma fructosamine (μmol/L) | 449 ± 25 | 494 ± 62 | 558 ± 103 |
Fasting plasma glucose (mmol/L) | 12.4 ± 0.4 | 14.4 ± 0.7 | 12.7 ± 1.6 |
Fasting plasma insulin (pmol/L) | 23 ± 7 | 26 ± 7 | 22 ± 4 |
Fasting hepatic glucose production (mg.kg -1 .min -1 ) | 7.4 ± 0.8 | 6.4 ± 0.5 | 8.2 ± 2.0 |
Clamp plasma glucose (steady state, mmol/L) | 5.7 ± 0.2 | 5.4 ± 0.2 | 5.4 ± 0.2 |
Clamp plasma insulin (steady state, pmol/L) | 320 ± 27 | 409 ± 33 | 327 ± 33 |
Insulin-stimulated whole body glucose uptake (mg.kg -1 .min -1 ) | 10.0 ± 2.3 | 9.5 ± 2.1 | 10.8 ± 2.8 |
Insulin-inhibited hepatic glucose production (mg.kg -1 .min -1 ) | 1.8 ± 0.2 | 1.2 ± 0.3 | 1.8 ± 0.1 |