Figure 3
From: Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins
The effects of exenatide and placebo on postprandial endothelial function. Endothelial function was measured before and after a single high-fat breakfast meal. Participants received placebo and exenatide on separate visits in a cross-over design. Post-meal PAT index was significantly higher (demonstrating improved endothelial function) during the exenatide phase compared with the placebo phase (p = 0.0002, adjusted for pre-meal PAT index, treatment sequence and glucose tolerance status) (Koska et al., Diabetes Care 2010, 33(5):1028-1030 [104]).