Figure 2
From: Postprandial hyperlipidemia, endothelial dysfunction and cardiovascular risk: focus on incretins
The effect of exenatide or placebo on postprandial concentrations of triglycerides (panel A) and apolipoprotein B-48 (apoB48, panel B) in serum, and remnant lipoprotein triglycerides (RLP-TG, panel C) and cholesterol (RLP-C, panel D) in plasma. The average effect of study medication (Drug) and the interaction between the effects of meal and drug (Drug*Time) were evaluated by repeated measures ANCOVA (adjusted for test sequence and glucose tolerance status). Symbols denote statistically significant (p < 0.05) difference between exenatide and placebo (‡) and versus pre-meal value (*) at each specified time points tested by post-hoc multiple comparison analyses. Number of subjects included in the analyses: triglycerides, n = 35; RLP-TG, n = 34; RLP-C, n = 31; apoB48, n = 28 (Schwartz et al., Atherosclerosis 2010, 212(1):217-222 [103]).