| Ach | Insulin | Ach + Insulin | SNP | ||||
---|---|---|---|---|---|---|---|---|
Groups | Max, % IC50(× 10-7M) | Max, % IC 50(× 10-10M) | Max, % IC50(× 10-7M) | Max, % IC50(× 10-8M) | ||||
SD+V | 116 ± 22 | 1.2 ± 0.8 | 17 ± 12 | 1.1 ± 1.2 | 116 ± 17 | 0.6 ± 0.5 | 103 ± 20 | 2.4 ± 1.7 |
H+V | 67 ± 13* | 1.3 ± 0.7 | 6 ± 7* | 140+122* | 98 ± 15 | 0.7 ± 0.6 | 83 ± 17 | 43 ± 3.1 |
H+C | 65 ± 15* | 1.8 ± 0.9 | 21 ± 10†| 3.3 ± 3.8†| 88 ± 13 | 1.3 ± 0.9 | 83 ± 16 | 1.7 ± 0.9 |
H+R | 73 ± 14* | 1.6 ± 0.9 | 22 ± 11†| 1.5 ± 1.8†| 98 ± 11 | 1.4 ± 0.9 | 88 ± 15 | 2.2 ± 1.2 |