Figure 2From: Protein Kinase C inhibition ameliorates functional endothelial insulin resistance and Vascular Smooth Muscle Cell hypersensitivity to insulin in diabetic hypertensive ratsThe typical tracing curves of pressure and diameter versus time during vasoreactivity which were measured by isovolumic myograph. A: The endothelium-dependent dose-response vasorelaxation. The vessels were contracted by phenylephrine (PE) to approximate pressures and relaxed by a series of doses of acetylcholine (ACh) (top panel) or a series of doses of ACh following by a series doses of insulin (bottom panel). B: The dose-response vasoconstriction in response to PE (top panel) and insulin with presentation of L-NAME (bottom panel).Back to article page